PUBLICATIONS (1986-2007)
  1. 1.Li G, Anderson RE, Tomita H, Adler R, Liu X, Zack DJ, Rajala RV. Nonredundant role of Akt2 for neuroprotection of rod photoreceptor cells from light-induced cell death. J Neurosci. 2007 Jan 3;27(1):203-11.
  2. 2.Sehgal R, Andres DJ, Adler R, Belecky-Adams TL. Bone morphogenetic protein 7 increases chick photoreceptor outer segment initiation.  Invest Ophthalmol Vis Sci. 2006 Aug;47(8):3625-34.
  3. 3.Moreira EF, Adler R. Effects of follistatin overexpression on cell differentiation in the chick embryo retina. Dev Biol. 2006 Oct 1;298(1):272-84. Epub 2006 Jun 27.
  4. 4.Canto-Soler MV, Adler R.  Optic cup and lens development requires Pax6 expression in the early optic vesicle during a narrow time window. Dev Biol. 2006 Jun 1;294(1):119-32.
  5. 5.Bradford RL, Wang C, Zack DJ, Adler R. (2005) Roles of cell-intrinsic and microenvironmental factors in photoreceptor cell differentiation. Dev Biol. 2005 Oct 1;286(1):31-45. .
  6. 6.Adler R. Challenges in the study of neuronal differentiation: a view from the embryonic eye. Dev Dyn. 2005 Nov;234(3):454-63. Review.
  7. 7.Wahlin KJ, Lim L, Grice EA, Campochiaro PA,Zack DJ, Adler R.(2004) A method for analysis of gene expression in isolated mouse photoreceptor and Muller cells. Mol Vis 10:366-375.
  8. 8.Hackam AS, Bradford RL, Zack DJ, Adler R. (2003) Gene discovery in the embryonic chick retina. Mol Vis 9:262-276.
  9. 9.Toy J, Norton JS, Jibodh SR, Adler R. (2002) Effects of Pax6 and Chx10 on the differentiation of photoreceptor and non-photoreceptor neurons. Invest Ophthlamol Vis Sci 43:3522-3529.
  10. 10.Belecky-Adams TL, Adler R, Beebe DC. (2002) Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation. Development 129:3795-3802.
  11. 11.Adler R, Belecky-Adams TL. (2002) The role of bone morphogenetic proteins in the differentiation of the ventral optic cup. Development 129:3161-3171.
  12. 12.Wahlin KJ, Adler R, Zack DJ, Campochiaro PA. (2001) Neurotrophic signaling in normal and degenerating rodent retinas. Exp Eye Res 73:693-701.
  13. 13.Adler R, Tamres A, Bradford RL, Belecky-Adams TL. (2001) Microenvironmental regulation of visual pigment expression in the chick retina. Dev Biol 15:454-464.
  14. 14.Belecky-Adams, T., and Adler, R. (2001) Developmental expression patterns of bone morphogenetic proteins, receptors and binding proteins in the chick retina. J Comp Neurol 430:562-572.
  15. 15.Toy J, Bradford RL, Adler R. (2000) Lipid-mediated gene expression into chick embryo retinal cells in ovo and in vitro. J Neurosci Meth 104:1-8.
  16. 16.Xie HQ, Adler R. (2000) Green cone opsin and rhodopsin regulation by CNTF and staurosporine in cultured chick photoreceptors. Invest Ophthalmol Vis Sci 41:4317-4323.
  17. 17.Adler, R. (2000) A model of retinal cell differentiation in the chick embryo. Prog Retina Eye Res 20:529-557.
  18. 18.Wahlin KJ, Campochiaro PA, Zack DJ, Adler R. (2000) Neurotrophic factors cause activation of intracellular signaling pathways in Muller cells and other cells of the inner retina, but not photoreceptors. Invest Ophthalmol Vis Sci 41:927-936.
  19. 19.Belecky-Adams TL, Scheurer D, Adler R. (1999) Activin family members in the developing chick retina expression patterns, protein distribution, and in vitro effects. Dev Biol 210:107-123.
  20. 20.Adler R, Curcio C, Hicks D, Price D, Wong F. (1999) Cell death in AMD. Mol Vis 5:31.
  21. 21.Adler R, Belecky-Adams T. (1998) Cell fate determination in the chick embryo retina. In: Cell Fate and Cell Lineage Determination (S. Moody, ed.) Academic Press, San Diego, pp 463-474.
  22. 22.Adler R. (1998) Cellular and molecular aspects of photoreceptor differentiation. In: Development and Organization of the Retina: From Molecules to Function, (L. Chalupa and B. Finlay, eds.) Plenum Press, New York, pp 13-26.
  23. 23.Cook B, Portera-Cailliau C, Adler R. (1998) Developmental neuronal death is not a universal phenomenon among cell types in the chick embryo retina. J Comp Neurol 396:12-36.
  24. 24.Weng J, Belecky-Adams T, Adler R, Travis GH. (1998) Identification of two rds/peripherin homologs in the chick retina. Invest Ophthalmol Vis Sci 39:440-443.
  25. 25.Belecky-Adams T, Tomarev S, Li H-S, Ploder L, McInnes RR, Sundin O, Adler R. (1997) Prox 1, Pax-6 and chx10 homeobox gene expression correlate with phenotypic fate of retinal precursor cells. Invest Ophthal Vis Sci 38:1293-1303.
  26. 26.Kumar R, Scheurer D, Duh E, Regemtulla A, Swaroop A, Adler R, Zack DJ. (1996) An Ap-1 cis-acting element mediates activation of the rhodopsin promoter by the bZIP transcription factor NRL. J Biol Chem 271:29612-29618.
    Belecky-Adams T, Cook B, Adler R. (1996) Correlations between terminal mitosis and differentiated fate of retinal precursor cells in vivo and in vitro: analysis with the "window-labeling technique. Dev Biol 178:304-315.
  27. 27.Saga T, Scheurer D, Adler R. (1996) Development and maintenance of outer segments by isolated chick embryo photoreceptor cells in culture. Invest Ophthalmol Vis Sci 37:561-573.
  28. 28.Adler R. (1995) Mechanisms of photoreceptor death in retinal degenerations: from the cell biology of the 1990's to the ophthalmology of the 21st century? Arch Ophthalmol 114:79-83.
  29. 29.Cook BE, Lewis GP, Fisher SK, Adler R. (1995) Apoptotic photoreceptor degeneration in experimental retinal detachment. Invest Ophthalmol Vis Sci 36:990-996.
  30. 30.Wang S-Z, Adler R. (1995) Chromokinesin: a DNA-binding, kinesin-like nuclear protein. J Cell Biol 128:761-768.
  31. 31.Stenkamp DL, Iuvone PM, Adler R. (1994) Photomechanical movements of cultured embryonic photoreceptors: regulation by exogenous neuromodulators and by a regulable source of endogenous dopamine. J Neurosci 14:3083-3096.
  32. 32.Stenkamp DL, Adler R. (1994) Cell type- and developmental stage-specific metabolism and storage of retinoids by embryonic chick retinal cells in culture. Exp Eye Res 58:675-687.
  33. 33.Portera-Cailliau C, Sung C-H, Nathans J, Adler R. (1994) Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa. Proc Natl Acad Sci USA 91:971-978.
  34. 34.Wang S-Z, Adler R. (1994) A novel basic-leucine zipper gene expressed in developing retina and lens. Proc Natl Acad Sci USA 91:1351-1355.
  35. 35.Stenkamp DL, Adler R. (1993) Photoreceptor differentiation of isolated retinal precursor cells includes the capacity for photomechanical responses. Proc Natl Acad Sci USA 90:1982-1986.
  36. 36.Adler R. (1993) Plasticity and differentiation of retinal precursor cells. In: International Review of Cytology (Friedlander M, ed), Academic Press, San Diego, Vol 146, pp. 145-190.
    Adler R. (1993) Determination of cellular types in the retina. Invest Ophthalmol Vis Sci 34:1677-1682.
  37. 37.Stenkamp DL, Gregory J, Adler R. (1993) Metabolism and biological effects of retinoids in RPE-free, glial-free, purified cultures of retina neurons and photo-receptors. Invest Ophthalmol Vis Sci 34:2425-2436.
  38. 38.Adler R. (1992) Cellular and Molecular Mechanisms Regulating Retinal Cell Differentiation In: The Visual System from Genesis to Maturity (Lent R, ed), Birkhauser, Inc. Boston, pp 21-35.
  39. 39.Paes de Carvalho R, Braas KM, Adler R, Snyder SH. (1992) Developmental regulation of adenosine A1 receptors, uptake sites and endogenous adenosine in the chick retina. Dev Brain Res 70:87-95.
  40. 40.Repka A, Adler R. (1992) Differentiation of retinal precursor cells born in vitro. Dev Biol 153:242-249.
  41. 41.Repka A, Adler R. (1991) Accurate determination of the time of cell birth using a sequential labeling technique with [3H] thymidine and bromodeoxyuridine ("window labeling"). J Histochem Cytochem 40:947-953.
  42. 42.Wang S-Z, Adler R, Nathans J. (1991) A visual pigment from chicken that resembles rhodopsin: amino acid sequence, gene structure, and functional expression. Biochem 31:3309-3315.
  43. 43.Adler R, Hewitt AT. (1991) Molecular factors regulating the survival and differentiation of photoreceptor cells. IN: Retinal Degenerations (Anderson RE, Hollyfield JG, LaVail MM, eds), CRC Press, Boca Raton, pp 79-86.
  44. 44.Murillo-Lopez F, Politi L, Adler R, Hewitt AT. (1991) Proteoglycan synthesis in cultures of murine retinal neurons and photoreceptors. Cell Mol Neurobiol 11:579-591.
  45. 45.Paes de Carvalho R, Braas KM, Snyder SH, Adler R. (1990) Analysis of adenosine immunoreactivity, uptake and release in purified cultures of chick embryo retinal neurons and photoreceptors. J Neurochem 55:1603-1611.
  46. 46.Werner M, Madreperla S, Lieberman P, Adler R. (1990) Expression of transfected genes by differentiated, postmitotic neurons and photoreceptors in primary cell cultures. J Neurosci Res 25:50-57.
  47. 47.Adler R. (1990) Preparation, enrichment and growth of purified cultures of neurons and photoreceptors from chick embryos and from normal and mutant mice. IN: Methods in Neurosciences, Vol. II (Conn PM, ed), Academic Press, Inc. Orlando, pp 134-150.
  48. 48.Iuvone PM, Avendano G, Johnson-Butler B, Adler R. (1990) Cyclic AMP-dependent induction of serotonin N-acetyltransferase activity in photreceptor-enriched chick retinal cell cultures: characterization and inhibition by dopamine. J Neurochem 55:673-682.
  49. 49.Madreperla SA, Edidin M, Adler R. (1989) Na+,K+- Adenosine triphosphatose polarity in retinal photoreceptors: a role for cyto-skeletal attachments. J Cell Biol 109:1483-1493.
  50. 50.Politi LE, Lee L, Wiggert B, Chader G, Adler R. (1989) Synthesis and secretion of interphotoreceptor retinoid-binding protein (IRBP) by isolated normal and rd mouse retinal photoreceptor neurons in culture. J Cell Physiol 141:682-690.
  51. 51.Hewitt AT, Lindsey JD, Carbott D, Adler R. (1990) Photoreceptor survival-promoting activity in interphotoreceptor matrix preparations: characterization and partial purification. Exp Eye Res 50:79-88.
  52. 52.Abrams L, Politi LE, Adler R. (1989) Differential susceptibility of isolated mouse retinal neurons and photo-receptors to kainic acid toxicity: in vitro analysis of cell survival and neurotransmitter-related activities. Invest Ophthalmol Vis Sci 30:2300-2308.
  53. 53.Threlkeld A, Adler R, Hewitt AT. (1989) Proteoglycan biosynthesis by chick embryo retina glial-like cells. Dev Biol 132:559-568.
  54. 54.Adler R, Hatlee M. (1989) Plasticity and differentiation of embryonic retinal cells after terminal mitosis. Science 243:391-393.
  55. 55.Madreperla SA, Adler R. (1989) Opposing microtubule- and actin-dependent forces in the devel-op-ment and main-te-nance of struc-tural polar-ity in retinal photoreceptors. Dev Biol 131:1-49-160.
  56. 56.Needham L, Adler R, Hewitt AT. (1988) Proteoglycan synthesis in purified cultures of retinal neurons and photoreceptors. Dev Biol 126:304-314.
  57. 57.Politi LE, Lehar M, Adler R. (1988) Development of neonatal mouse retinal neurons and photoreceptors in low density cell cultures. Invest Ophthalmol Vis Sci 29:534-543.
  58. 58.Politi L, Adler R. (1988) Selective failure of long term survival of isolated photoreceptors from both homozygous and heterozygous rd (retina degeneration) mice. Exp Eye Res 47:269-282.
  59. 59.Madreperla SA, Adler R. (1988) Opposing microtubule-and actin-dependent forces in the development and maintenance of structural polarity in retinal photoreceptors. Dev Biol 131:149-160.
  60. 60.Adler R. (1988) Trophic factors in neural development. In: Handbook of Human Growth and Developmental Biology, (E. Meisami and P. S. Timiras eds.), CRC Press, Inc., Boca Raton, pp 67-74.
  61. 61.Politi LE, Adler R. (1987) Selective destruction of photoreceptor cells by anti-opsin antibodies. Invest Ophthalmol Vis Sci 28:118-125.
  62. 62.Politi LE, Adler R, Whittum-Hudson J. (1987) Differential sensitivity of cultured retinal neurons and photoreceptors to herpes simplex infection. Exp Eye Res 44:923-937.
  63. 63.Adler R. (1987) Nature and nurture in the differentia-tion of retinal photoreceptors and neurons. Cell Differentiation 20:183-188.
  64. 64.Adler R. (1987) Cell culture systems for purified retinal neurons and photoreceptors. In: Model Systems in Develop-ment and Aging of the Nervous System, (A. Vernadakis, A. Privat, J. Lauder, P. Timiras, E. Giacobini eds.), Martinus Nijoff Publ., Boston, pp 3-17.
  65. 65.Adler R. (1987) In vitro techniques for the investigation of trophic factors active on CNS neurons. In: Handbook of Nervous System and Muscle Factors, (J. R. Perez-Polo, ed.), CRC Press, Inc., Florida, pp 151-173.
  66. 66.Politi LE, Adler R. (1986) Generation of enriched popula-tions of cultured photoreceptor cells. Invest Ophthal-mol Vis Sci 27:656-665.
  67. 67.Adler R. (1986) Developmental predetermination of the structural and molecular polarization of photoreceptor cells. Dev Biol 117:520-527.
  68. 68.Adler R. (1986) Trophic interactions in retina development and in retinal degenerations: in vivo and in vitro studies. In: The Retina: A Model for Cell Biology, Part I (R. Adler and D. Farber, eds.), Academic Press, Orlando, pp 112-150.
  69. 69.Adler R. (1986) The differentiation of retinal photoreceptors and neurons in vitro. In: Progress in Retinal Research (N. Osborne and G. Chader, eds.), Pergamon Press, London, Vol. VI, pp 1-27.
  70. 70.Farber D, Adler R. (1986) Issues and questions in cell biology of the retina. In: The Retina, A Model for Cell Biology Studies, Part I, (R. Adler and D. Farber, eds.), Academic Press, Orlando, pp 2-16.
 
Publications