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publication

Selected Publications:
On Tissue Engineering and Stem Cell Engineering:

  • Feng Q, Chai C, Jiang XS, Leong KW, Mao HQ. Expansion of engrafting human hematopoietic stem/progenitor cells in three-dimensional scaffolds with surface-immobilized fibronectin. Journal of Biomedical Materials Research, Part A. In press (2006). [PMID: 16739181, pdf]
  • Chua KN, Lim WS, Zhang PC, Lu HF, Wen J, Ramakrishna S, Leong KW, Mao HQ, Stable Immobilization of Rat Hepatocyte Spheroids on Galactosylated Nanofiber Scaffold. Biomaterials 26(15):2537-2547 (2005). [Times cited: 8] [PMID: 15585256, pdf]
  • Lu HF, Chua KN, Zhang PC, Lim WS, Ramakrishna S, Leong KW, Mao HQ, Three-dimensional co-culture of rat hepatocyte spheroids and NIH/3T3 fibroblasts enhances hepatocyte functional maintenance, Acta Biomaterialia, 1(5): 399-410 (2005). [PMID: 16701821, pdf]
  • Lu HF, Lim WS, Zhang PC, Wang J, Tang ZQ, Chia SM, Yu H, Leong KW, Mao HQ, Galactosylated PVDF membrane promotes hepatocyte attachment and functional maintenance. Biomaterials. 24(27): 4893-4903 (2003). [Times cited: 8] [PMID: 14559002, pdf]
  • Yin C, Chia SM, Quek CH, Yu H, Zhuo RX, Leong KW, Mao HQ. Microcapsules with improved mechanical stability for hepatocyte culture. Biomaterials. 24(10):1771-1780 (2003). [Times cited: 16] [PMID: 12593959, pdf]
  • Yin C, Ying L, Zhang PC, Zhuo RX, Kang ET, Leong KW, Mao HQ. High density of immobilized galactose ligand enhances hepatocyte attachment and function. Journal of Biomedical Materials Research. 67A(4): 1093-1104 (2003). [Times cited: 13] [PMID: 14624494, pdf]

On Non-viral Gene Delivery:

  • Jiang X, Dai H, Leong KW, Goh SH, Mao HQ, Yang YY, Chitosan-g-PEG/DNA complexes deliver gene to the rat liver via intrabiliary and intraportal infusions, Journal of Gene Medicine, 8(4): 477-487 (2006). [PMID: 16389625, pdf]
  • Mao HQ, Leong KW, Design of poly(phosphoester) nanoparticles for nonviral gene therapy. Advances in Genetics 53: 275-306 (2005). [PMID: 16243068, pdf]
  • Chew JL, Wolfowicz CB, Mao HQ, Leong KW, Chua KY. Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice. Vaccine. 21(21-22): 2720-2729 (2003). [Times cited: 16] [PMID: 12798609, pdf]
  • Zhao Z, Wang J, Mao HQ, Leong KW. Polyphosphoesters in drug and gene delivery. Advanced Drug Delivery Reviews. 55(4): 483-499 (2003). [Times cited: 24] [PMID: 12706047, pdf]
  • Wang J, Zhang PC, Mao HQ, Leong KW. Enhanced gene expression in mouse muscle by sustained release of plasmid DNA using PPE-EA as a carrier. Gene Therapy. 9(18): 1254-1261 (2002). [Times cited: 36] [PMID: 12215893, pdf]
  • Wang J, Mao HQ, Leong KW. A novel biodegradable gene carrier based on polyphosphoester. Journal of the American Chemical Society. 123(38): 9480-9481 (2001). [Times cited: 42] [PMID: 11562246, pdf]
  • Mao HQ, Roy K, Truong-Le VL, Janes K, Lin KY, Wang Y, August JT, Leong KW. Chitosan-DNA nanoparticles as gene delivery vehicles. Journal of Controlled Release. 70(3): 399-421 (2001). [Times cited: 133] [PMID: 11182210, pdf]
  • Roy K, Mao HQ, Huang SK, Leong KW. Oral gene delivery with chitosan-DNA nanoparticles generates immunological protection in a murine model of peanut allergy. Nature Medicine. 5(4): 387-391 (1999). [Times cited: 282] [PMID: 10202926, pdf]
  • Leong KW, Mao HQ, Truong-Le VL, Roy K, Walsh SM, August JT. DNA nanospheres as non-viral gene delivery vehicles. Journal of Controlled Release. 53(1): 183-193 (1998). [Times cited: 133] [PMID: 9741926, pdf]

On Biodegradable Polymers:

  • Mao HQ, Shipanova I, Zhao Z, Dang W, Brown A, Leong KW. Biodegradable poly(terephthalate-co-phosphate)s: Synthesis, characterization and drug release properties. Journal of Biomaterials Science-Polymer Edition. 16(2): 135-161 (2005). [PMID: 15794482, pdf]
  • Wan AC, Mao HQ, Wang S, Phua SH, Lee GP, Pan J, Lu S, Wang J, Leong KW. Poly(phosphoester) ionomers as tissue-engineering scaffolds. Journal of Biomedical Materials Research. 70B(1):91-102 (2004). [Times cited: 2] [PMID: 15199588, pdf]
  • Hu JJ, Yin C, Mao HQ, Tamada K, Knoll WG, Functionalization of poly(ethylene terephthalate) film by pulsed plasma deposition of maleic anhydride. Advanced Functional Materials. 13(9): 692-697 (2003). [Times cited: 4] [pdf]