After more than four years in a nursing home on a regimen that required him to take up to a dozen pills a day, quadriplegic Robert Arthur Williams sought to live in a more independent setting. "To do that, they told me I'd have to find a way to have my medications dispensed to me whenever I needed them, 24 hours a day," said Williams, a 40-year-old former welder-mechanic who lost the use of his limbs in 1997 when he was struck by a car while crossing a street. For help, Williams turned to the Volunteers for Medical Engineering, a Baltimore organization that provides customized equipment and devices to people with unusual medical problems.

Robert Arthur Williams, a quadriplegic, needed a way to take his own medication. Ross Whitaker and Paul Stemniski were members of the JHU team that designed and built him a machine.

VME administrators, in turn, referred the request to students in this year's Senior Design Project course in the Department of Mechanical Engineering at Johns Hopkins.

Four students enrolled in the two-semester course were asked to design, build and test a device that would allow Williams to take his own medication, as needed, despite his severely limited mobility. The students could spend no more than $8,000 to produce their prototype. Shortly after commencement, two of the students delivered the device to Williams.

"This project had so many challenging aspects involved in it -- electronics, mechanics, ergonomics and computer programming," said Ross Whitaker, a member of the design team. "We got a whole array of engineering experience while working on it."

The computer-guided pill-dispensing machine that the students designed and constructed will enable Williams to lead a more independent life. Using a mouth stick, he will be able to order one of up to 12 different medications stored inside the machine. Then, when Williams taps a "slam switch" (he has limited mobility in his right arm), the machine will dispense a pill through a tube leading to his mouth.

While the students were working on the machine, Williams was able to move out of a nursing home and into a three-bedroom house with two companions who assist with his care. "With this machine, I'll be able to take medicine for pain or muscle spasms at 3 in the morning without waking up one of my helpers," he said. "I'll be able to take care of myself for longer periods of time now."

In the finished device, Williams' medicine is stored inside a locked box that houses 12 waterwheel-shaped dispensers. Each wheel has 15 pill compartments, enabling the device to store up to 180 pills. When Williams needs a particular pill, he can use his mouth stick to press a series of numbered buttons mounted on the front of the unit. First, he enters a security code, then the number that corresponds to the medication he wishes to take. Next, when he taps the slam switch, a computer signals the appropriate container to turn, dropping the pill into a Teflon-coated chute. Gravity causes the pill to slide down the chute and into a flexible tube leading to Williams' mouth. Water bottles and straws mounted on his wheelchair and near his bed help him swallow the medication. If he needs additional pills, he can repeat the sequence.

"It required a lot of work, but I think the students did a very thorough job on it," said Alan Markham, a retired engineer and VME member who monitored the project. "The students put a lot of ingenious thought into it."

"This was a very challenging project but also a very rewarding one," said Paul Stemniski, another of the student inventors. "There was a lot of satisfaction in knowing that we were helping Robert."

Stemniski, who majored in mechanical engineering, plans to begin graduate engineering studies in the fall at the University of Michigan. Whitaker, a biomedical engineering major, is joining St. Jude Medical as a field engineer. Their team also included Mark O'Leary and Yo-Rhin Rhim, both mechanical engineering majors. Rhim will begin a master's degree in mechanical engineering at Johns Hopkins in the fall.

The pill-dispensing device was one of 11 projects completed this year by students in the Senior Design Project course. The class is taught by Andrew F. Conn, a Johns Hopkins graduate with more than 30 years' experience in public and private research and development. Each team of three or four students, working within budgets of up to $10,000, had to design a device, purchase or fabricate the parts and assemble the final product. Corporations, government agencies and nonprofit groups provided the assignments and funding.