Name Dr. MATTHEW E. HELTON
e-mail mhelton@jhu.edu
Homepage
Education Postdoc: Chemistry - Johns Hopkins University / University of Basel
- Date: August 2000 - February 2004
- Funding: National Institutes of Health Postdoctoral Fellowship
- Advisors: Professor Kenneth D. Karlin (JHU) / Professor Andreas D. Zuberbühler (UB)

Ph.D.: Chemistry - University of New Mexico
- Date: August 1995 - August 2000
- Advisor: Professor Martin L. Kirk
- Thesis: Electronic Structure Models for Pyranopterin Enzyme Active Sites: A Spectroscopic Investigation

B.S.: Chemistry (Area of Concentration: Math/Physics) - Morehead State University
- Date: August 1991 - May 1995
- Advisor: Professor Michael R. Adams (Presently with Xavier University of Louisiana)
- Thesis: Synthesis and Reactivity of Mixed Bridge Phosphido-Diiron Complexes
Research
Publications
  • Helton, M.E.; Kirk, M.L. "A Model for Ferricyanide Inhibited Sulfite Oxidase" Inorg. Chem. 1999, 38, 4384-4385.

  • Inscore, F.E.; McNaughton, R.; Westcott, B.L.; Helton, M.E.; Jones, R.; Dhawan, I.K.; Enemark, Kirk, M.L. "Spectroscopic Evidence for a Unique Bonding Interaction in Oxo-Molybdenum Dithiolate Complexes: Implications for σ Electron Transfer Pathways in the Pyranopterin Dithiolate Centers of Enzymes" Inorg. Chem. 1999, 38, 1401-1410.

  • Helton, M.E.; Gruhn, N.; McNaughton, R.L.; Kirk, M.L. "Control of Oxo-Molybdenum Reduction and Ionization Potentials by Dithiolate Donors" Inorg. Chem. 2000, 39, 2273-2278.

  • Helton, M.E.; Pacheco, A.; McMaster, J.; Enemark, J.H.; Kirk, M.L. " An MCD Spectroscopic Study of the Molybdenum Active Site in Sulfite Oxidase: Insight into the Role of Coordinated Cysteine" J. Inorg. Biochem. 2000, 80, 227-233.

  • McNaughton, R.L.; Helton, M.E.; Rubie, N.D.; Kirk, M.L. "The Oxo-Gate Hypothesis and DMSO Reductase: Implications for a Psuedo-σ Bonding Interaction Involved in Enzymatic Electron Transfer" Inorg. Chem. 2000, 39, 4386-4387.

  • Helton, M.E.; Gebhart, N.L.; Davies, E.S.; McMaster, J.; Garner, C.D.; Kirk, M.L.; "Thermally Driven Intramolecular Charge Transfer in an Oxo-Molybdenum Dithiolate Complex" J. Am. Chem. Soc. 2001, 123, 10389-10390.

  • Zhang, C.X.; Liang, H-C.; Kim, E-I.; Shearer, J.; Helton, M.E.; Kim, E.; Kaderli, S.; Incarvito, C.; Zuberbühler, A.D.; Rheingold, A.L.; Karlin, K.D. "Tuning Copper-Dioxygen Reactivity and Exogenous Substrate Oxidations via Alterations in Ligand Electronics" J. Am. Chem. Soc. 2003, 125, 634-635.

  • Helton, M.E.; Chen, P.; Paul, P.P.; Tyeklár, Z.; Sommer, R.D.; Zhakarov, L.; Rheingold, A.L.; Solomon, E.I.; Karlin, K.D. "Reaction of Elemental Sulfur with a Copper(I) Complex, forming a trans-μ-1,2 End-on Disulfide Complex: New Directions in Copper-Sulfur Chemistry" J. Am. Chem. Soc. 2003, 125, 1160-1161.

  • Kim, E.; Helton, M.E.; Wasser, I.M.; Karlin, K.D.; Lu, S.; Huang, H-W.; Moënne-Loccoz, P.; Incarvito, C.D.; Rheingold, A.L.; Honecker, M.; Kaderli, S.; Zuberbühler, A.D. "Superoxo, μ-peroxo and μ-oxo Complexes Derived from Heme/O2 and Heme-copper/O2 Reactivity Studies: Copper-Ligand Influences in Synthetic Model Reactivity Studies of the Cytochrome c Oxidase Binuclear Active Site" Proceedings of the National Academy of Science, USA 2003, 100, 3623-3628.

  • Chen, P.; Fujisawa, K.; Helton, M.E.; Karlin, K.D.; Solomon, E.I. "Spectroscopy and Bonding in End-On and Side-On Cu2(S2) Cores: Comparison to Peroxide Analogues" J. Am. Chem. Soc. 2003, 125, 6394-6408.

  • Kirk, M.L.; Helton, M.E.; McNaughton, R.L. "The Electronic Structure and Spectroscopy of Metallo-Dithiolene Complexes" Progress in Inorganic Chemistry, 2003, 52, 111-212.

  • McNaughton, R.L.; Helton, M.E.; Cosper, M.M.; Enemark, J.H.; Kirk, M.L. "Nature of the Oxomolybdenum-Thiolate π Bond: Implications for Mo-S Bonding in Sulfite Oxidase and Xanthine Oxidase" Manuscript Submitted.
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