BIOGRAPHICAL SKETCH

    EDUCATION - POSTDOCTORAL TRAINING:
  • B.S., 1970, (cum laude), Stanford University
  • Ph.D., 1975, Columbia University, New York
  • Postdoctoral Fellow, 1975-1977, Cambridge University, England


    Positions and Honors:
  • 1977-1983 Assistant Professor: Department of Chemistry, SUNY at Albany, Albany, NY
  • 1983-1987 Associate Professor: Department of Chemistry, SUNY at Albany, Albany, NY
  • 1987-1990 Professor: Department of Chemistry, SUNY at Albany, Albany, NY
  • 1990-present Professor: Department of Chemistry, The Johns Hopkins University, Baltimore, MD

  • Apppointed to Ira Remsen Chair in Chemistry, Johns Hopkins University, May 1999.
  • Elected Chair, 1998 Metals in Biology Gordon Research Conference
  • "MERIT" Award, 1993- 2003 , National Institute of General Medical Sciences (NIH).
  • Fellow, American Association for the Advancement of Science (AAAS) - elected October, 1992.
  • 1991 Buck-Whitney Award (ACS Eastern New York Section Research Award)
  • University "Excellence in Research" Award, SUNY at Albany, 1988.
  • General Electric Visiting Faculty Research Fellow, GE R&D Center, Schenectady, NY, 1986-87.

    Professional Activities (selected):
  • Editor-in-Chief: Progress in Inorganic Chemistry (Wiley-Interscience), 1992-present.
  • Secretary/Head of the International Organizing Committee for the biennial International Conference on Bioinorganic Chemistry (ICBIC), Permanent member since 1985; elected Secretary, 2001.
  • Society for Biological Inorganic Chemistry (SBIC). Treasurer (elected), 1999-2003.
  • Advisory Board, Petroleum Research Fund, American Chemical Society (PRF-ACS), 1998-2001
  • Editorial Boards: Accounts of Chemical Research ('03-'05), Progress in Inorganic Chemistry ('89-'91); Journal of Inorganic Biochemistry ('92- ); Inorganic Chemistry ('95-'97); Journal of Biological Inorganic Chemistry ('96-'99).
  • NIH Study Section: Review Panel Member, Metallobiochemistry (BMT), 1988-1992.
  • American Chemical Society: 1996 Chairman (elected) of Bioinorganic Subdivision, Division of Inorg, Chem.
  • Organizer/Chairman: 1998 Gordon Research Conf. on Metals in Biology, Chair (elected); Johns Hopkins University Symposium, Copper Coordination Chemistry: Bioinorganic Perspectives, August 3-7, 1992; Fourth International Conference on Bioinorganic Chemistry (ICBIC-4), July, 1989, Cambridge, MA.

    Recent Invited Symposia Lectures:
    3rd International Meeting on Copper Homeostasis and Its Disorders: Molecular and Cellular Aspects. Ischia, Italy, October 4-8, 2002. Invited Lecturer.
    Tenth International Conference on Bioinorganic Chemistry (ICBIC-10), Florence, Italy, August 26-31, 2001. Session Lecturer.
    Symposium Honoring the Scientific Achievements of Gerald T. Babcock: Physical Approaches to Biochemical Problems. Michigan State Univ., June 1-2, 2001.
    Edward I. Solomon ACS National Award Symposium, ACS National Meeting (Inorganic Division), San Diego, CA, April 1-5, 2001, INOR 14.
    Symposium on Oxygen Activation by Metalloproteins and Their Models, Pacifichem 2000 (ACS Pacific Basins Mtg.) , Dec. 14-19, 2000, Honolulu, Hawaii.
    Inorganic Biochemistry Summer Workshop (IBSW2000), U. Georgia, July 29 - August 9, 2000. Lecture on Bioinorganic Synthetic Modeling.
    Symposium on Bioinspired Catalysis and Functional Modeling, ACS National. Meeting (Inorganic Division), New Orleans, LA, Aug. 22-26, 1999, INOR 278.
    Eighth International Conference on Bioinorganic Chemistry (ICBIC-8), Yokohama, Japan, July 27-Aug. 1, 1997. Plenary Lecturer
    Metals in Biology Gordon Research Conference, Ventura, CA, Jan 19-24, 1997.

    Co-Invited Editor:
    Barton, Jacqueline K.; Karlin, Kenneth D.; Editors. “Bio-Inorganic Chemistry: New Advances, New Directions and New Investigators?[In: Curr. Opin. Chem. Biol., 2001; 5(2)], 62 pp.



    Research Support:


    R37 GM 28962 (K. D. Karlin, PI)
    04/01/93 - 03/31/03
    NIH Bioinorganic Copper Coordination Chemistry
    The overall goals of this project are to study copper coordination chemistry relevant to metalloenzyme active sites, including those that process dioxygen and nitrogen oxides. Thus, investigations include the design, synthesis, and characterization of copper(I) complexes, their kinetics and thermodynamics of O2-interaction structure and spectroscopy of adducts, and mechanisms of reactions with substrates. The overall goals also encompass copper cluster compounds and their interactions with sulfur.
    Role: Principal Investigator

    R01 GM 60353 (K. D. Karlin, PI)
    04/01/01 - 03/31/04
    NIH Heme/Copper and Heme/Non-Heme Iron O2 and NO Reactivity
    The investigative efforts include synthetic modeling of cytochrome c oxidase and nitric oxide reductase, by studying the reactions of synthetic heme/copper and heme/non-heme iron systems with O2 and NO.
    Role: Principal Investigator

    CHE 0089168 (G. J. Meyer, PI)
    09/01/01 - 08/31/06
    National Science Foundation CRAEMS: Environmental Redox-Mediated Dehalogenation Chemistry
    The project is a collaborative research effort, with G. J. Meyer (Chemistry Dept.) as PI and four other Co-PI's from the Chemistry Dept. or Department of Geography & Environmental Engineering at Johns Hopkins. The overall program seeks to develop fundamental chemistry relevant to the destruction of organohalides, representing, in particular, serious pollutants in groundwater. Our own particular focus is to develop basic chemistry with copper ion complexes, to effect either the reductive (with copper(I)) or oxidative (with copper(I) plus dioxygen) dehalogenation of organohalide substrate compounds.
    Role: Co-Principal Investigator
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