|
 |
| For
publications of
before 2004. |
 Screening
for Microsatellite Instability Identifies Frequent
3'-Untranslated Region Mutation of the RB1-Inducible Coiled-Coil
1 Gene in Colon Tumors |
| Bogdan C. Paun,
Yulan Cheng, Barbara A. Leggett, Joanne Young, Stephen J.
Meltzer, Yuriko Mori |
|
PLoS One. 2009 Nov 2;4(11):e7715. |
|
Chromosomal abnormalities and novel disease-related regions in
progression from Barrett’s esophagus to esophageal
adenocarcinoma |
| Akagi
T, Ito T,
Kato M,
Jin Z,
Cheng Y, Kan
T, Yamamoto G, Olaru
A, Kawamata
N, Boult J, Soukiasian
J, Miller C, Ogawa
S, Meltzer
SJ, Koeffler HP |
|
International Journal of Cancer, June 2009,[Epub
ahead of print] |
|
A
Multicenter, Double-Blinded Validation Study of Methylation
Biomarkers for Progression Prediction in Barrett’s
Esophagus |
| Jin Z, Cheng Y, Zheng Y, Gu J, Sato F, Olaru AV, Paun B, Yang J, Kan T, Ito T,
Hamilton JP, Selaru FM, Mori Y, Agarwal R, David S, Abraham JM,
Wolfsen H, Shaheen NJ, Wang J, Canto M, Washington K, Romero Y,
Wang KK, Feng Z, Sampliner RD, Meltzer SJ. |
|
Cancer Res. 2009, May 15; 69(10): 4112-4115. |
|
The
miR-106b-25 polycistron, activated by genomic amplification,
functions as an oncogene by suppressing p21 and Bim |
|
Kan T, Sato F, Ito T, Matsumura N, David S, Cheng Y, Agarwal R,
Paun BC, Jin Z, Olaru AV, Selaru FM, Hamilton JP, Yang J,
Abraham JM, Mori Y, Meltzer SJ. |
|
Gastroenterology. 2009 May;136(5):1689-700. |
|
MicroRNA-21 is overexpressed in human cholangiocarcinoma and
regulates programmed cell death 4 and tissue inhibitor of
metalloproteinase 3. |
| Selaru FM, Olaru
AV, Kan T, David S, Cheng Y, Mori Y, Yang J, Paun B, Jin Z,
Agarwal R, Hamilton JP, Abraham J, Georgiades C, Alvarez H,
Vivekanandan P, Yu W, Maitra A, Torbenson M, Thuluvath PJ, Gores
GJ, LaRusso NF, Hruban R, Meltzer SJ. |
|
Hepatology. 2009 May;49(5):1595-601. |
|
Three-tiered
Risk Stratification Model to Predict Progression in Barrett’s
Esophagus Using Epigenetic and Clinical Features |
| Sato F, Jin Z,
Schulmann K, Wang J, Greenwald B, Ito T, Kan T, Hamilton JP,
Yang J, Paun B, David S, Olaru A, Cheng Y, Mori Y, Abraham
JM, Yfantis H, Wu T, Fredericksen M, Wang K, Canto M,
Romero Y, Feng Z, Meltzer SJ. |
| PLoS ONE. 2008 Apr 2; 3(4):e1890. |
|
PTTG1
increases cell motility and promotes lymph node metastasis in
esophageal squamous cell carcinoma |
| Ito T, Shimada Y,
Kan T, David S, Cheng Y, Mori Y, Agarwal R, Paun B, Jin Z, Olaru
A, Hamilton JP, Yang J, Abraham JM, Meltzer SJ, Sato F |
| Cancer Research.
2008 May 1;68(9):3214-3224 |
|
Hypermethylation
of the AKAP12 Promoter is a Biomarker of Barrett's-Associated
Esophageal Neoplastic Progression |
| Jin Z, Hamilton
JP, Yang J, Mori Y, Olaru A, Sato F, Ito T, Kan T, Cheng Y, Paun
B, David S, Agarwal R, Abraham JM, Meltzer SJ. |
| Cancer Epidemiology
Biomarkers & Prevention. 2008, Jan 1; 17 111-117. |
|
Hypermethylation
of the somatostatin promoter is a common, early event in human
esophageal carcinogenesis.
|
|
Jin Z, Mori Y, Hamilton JP, Olaru A, Sato F, Yang J, Ito T, Paun
B, Kan T, Agarwal R, Meltzer SJ. |
|
Cancer. 2008 Jan 1;112(1):43-9. |
|
Novel
Decapeptides that Bind Avidly and Deliver Radioisotope to Colon
Cancer Cells |
| John
M. Abraham, Fumiaki Sato, Yulan Cheng, Bogdan Paun, Takatsugu
Kan, Alexandru Olaru, Zhe Jin, Jian Yang, Rachana
Agarwal, Stefan David, James P. Hamilton, Tetsuo Ito, Yuriko
Mori, Stephen J. Meltzer |
| 2007 PLoS ONE 2(10): e964.
doi:10.1371/journal.pone.0000964 |
|
Hypermethylation
of Tachykinin-1 is Associated with a Poor Prognosis in Human
Esophageal Squamous Cell Carcinoma. |
|
Jin Z, Olaru A, Yang J, Sato F, Cheng
Y, Mori Y, Mantzur C, Paun B, Hamilton JP, Ito T, Kan T, Wang S,
David S, Agarwal R, Beer DG, Abraham JM, Meltzer SJ. |
|
Clin Cancer Res. 2007 Nov 1;13(21):6293-300 |
|
Rarity
of somatic mutation and frequency of normal sequence variation
detected in sporadic colon adenocarcinoma using
high-throughput cDNA sequencing. |
| Kan T, Paun B,
Mori Y, Sato F, Jin Z, Hamilton JP, Ito T, Cheng Y, David S,
Olaru A, Yang J, Agarwal R, Abraham JM, Meltzer SJ. |
| Bioinformatics &
Biology Insights 2007: 1 1-16 |
|
Hypermethylation
of the nel-like 1 gene is a common and early event and is
associated with a poor prognosis in early-stage esophageal
adenocarcinoma. |
|
Jin Z, Mori Y, Yang J, Sato F, Ito
T, Cheng Y, Paun B, Hamilton JP, Kan T, Olaru A, David S,
Agarwal R, Abraham JM, Beer D, Montgomery E, Meltzer SJ. |
| Oncogene. 2007 Sep
20;26(43):6332-40. |
|
Reprimo
methylation is a potential biomarker of Barrett's-Associated
esophageal neoplastic progression. |
|
Hamilton JP, Sato F, Jin Z, Greenwald BD, Ito T, Mori Y, Paun
BC, Kan T, Cheng Y, Wang S, Yang J, Abraham JM, Meltzer SJ.
|
|
Clin Cancer Res. 2006 Nov 15;12(22):6637-42. |
|
A
genome-wide search identifies epigenetic silencing of somatostatin, tachykinin-1, and 5 other genes in colon cancer. |
| Mori Y, Cai K,
Cheng Y, Wang S, Paun B, Hamilton JP, Jin Z, Sato F, Berki AT,
Kan T, Ito T, Mantzur C, Abraham JM, Meltzer SJ. |
| Gastroenterology.
2006 Sep;131(3):797-808 |
|
RAB32 hypermethylation and
microsatellite instability in gastric and endometrial
adenocarcinomas. |
| Shibata D, Mori Y,
Cai K, Zhang L, Yin J, Elahi A, Hamelin R, Wong YF, Lo WK, Chung
TK, Sato F, Karpeh MS Jr, Meltzer SJ. |
| Int J Cancer. 2006
Aug 15;119(4):801-6. |
|
Thapsigargin resistance in human
prostate cancer cells. |
| O'Neill
JP, Velalar CN, Lee DI, Zhang B, Nakanishi T, Tang Y, Selaru F,
Ross D, Meltzer SJ, Hussain A. |
| Cancer.
2006 Aug 1;107(3):649-59. |
|
Promoter methylation and response to
chemotherapy and radiation in esophageal cancer. |
| Hamilton JP, Sato
F, Greenwald BD, Suntharalingam M, Krasna MJ, Edelman MJ, Doyle
LA, Berki AT, Abraham JM, Mori Y, Kan T, Mantzur C, Paun T, Wang
S, Ito T, Jin Z, Meltzer SJ. |
| Clin Gastroenterol
Hepatol. 2006 Jun;4(6):701-8. |
|
Transcriptional profiling suggests that Barrett's metaplasia is
an advanced intermediate stage in esophageal adenocarcinoma. |
| Wang S, Zhan
M, Yin J, Abraham JM, Mori Y, Sato F, Xu Y, Olaru A, Li H,
Schulmann K, Sterian A, Kan T, Hamilton JP, Chai K, Deacu E,
Berki AT, Greenwald BD and Meltzer SJ. |
| Oncogene 2006
Jun 1; 25(23):3346-3356. |
|
Polo-like kinase and survivin are
esophageal tumor-specific promoters. |
| Sato F, Abraham JM,
Yin J, Kan T, Ito T, Mori Y, Hamilton JP, Jin Z, Cheng Y, Paun
B, Berki AT, Wang S, Shimada Y, Meltzer SJ. |
| Biochem Biophys Res
Commun. 2006 Apr 7;342(2):465-71. |
|
Aberrant promoter methylation of
multiple genes during multistep pathogenesis of colorectal
cancers. |
|
Takahashi T, Shigematsu H, Shivapurkar N, Reddy J, Zheng Y, Feng
Z, Suzuki M, Nomura M, Augustus M, Yin J, Meltzer SJ, Gazdar AF. |
|
Int J Cancer. 2006 Feb 15;118(4):924-31. |
|
Mutational and LOH analyses of
the chromosome 4q region in esophageal adenocarcinoma. |
| Sterian A, Kan T,
Berki AT, Mori Y, Olaru A, Schulmann K, Sato F, Wang S, Paun B,
Cai K, Hamilton JP, Abraham JM, Meltzer SJ. |
| Oncology. 2006;70(3):168-72. Epub
2006 Jul 7. |
|
A new specific gene expression in
squamous cell carcinoma of the esophagus detected using
representational difference analysis and cDNA microarray. |
| Kan T, Yamasaki S,
Kondo K, Teratani N, Kawabe A, Kaganoi J, Meltzer SJ, Imamura M,
Shimada Y. |
| Oncology.
2006;70(1):25-33. |
|
Esophageal cancer epidemiology in
blacks and whites: racial and gender disparities in incidence,
mortality, survival rates and histology. |
| Baquet CR,
Commiskey P, Mack K, Meltzer S, Mishra SI. |
| J Natl
Med Assoc. 2005 Nov;97(11):1471-8. |
|
The molecular signature of normal
squamous esophageal epithelium identifies the presence of a
field effect and can discriminate between patients with
Barrett's esophagus and patients with Barrett's-associated
adenocarcinoma. |
| Brabender J,
Marjoram P, Lord RV, Metzger R, Salonga D, Vallbohmer D, Schafer
H, Danenberg KD, Danenberg PV, Selaru FM, Baldus SE, Holscher
AH, Meltzer SJ, Schneider PM. |
|
Cancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2113-7.
|
|
Molecular phenotype of inflammatory
bowel disease-associated neoplasms with microsatellite
instability |
| Schulmann K, Mori
Y, Croog V, Yin J, Olaru A, Sterian A, Sato F, Wang S, Xu Y,
Deacu E, Berki AT, Hamilton JP, Kan T, Abraham JM, Schmiegel W,
Harpaz N, Meltzer SJ. |
| Gastroenterology. 2005
Jul;129(1):74-85. |
|
Aberrant methylation of Reprimo in
human malignancies. |
| Takahashi T,
Suzuki M, Shigematsu H, Shivapurkar N, Echebiri C, Nomura M,
Stastny V, Augustus M, Wu CW, Wistuba II, Meltzer SJ, Gazdar AF.
|
| Int J Cancer.
2005 Jul 1;115(4):503-10. |
|
Inactivation of p16, RUNX3, and HPP1
occurs early in Barrett's-associated neoplastic progression and
predicts progression risk. |
|
Schulmann K,
Sterian A, Berki A, Yin J, Sato F, Xu Y, Olaru A, Wang S, Mori
Y, Deacu E, Hamilton J, Kan T, Krasna MJ, Beer DG, Pepe MS,
Abraham JM, Feng Z, Schmiegel W, Greenwald BD, Meltzer SJ. Oncogene. 2005 Jun
9;24(25):4138-48. |
|
Prediction of survival in patients
with esophageal carcinoma using artificial neural networks. |
| Sato F,
Shimada Y, Selaru FM, Shibata D, Maeda M, Watanabe G, Mori Y,
Stass SA, Imamura M, Meltzer SJ. |
|
Cancer. 2005 Apr
15;103(8):1596-605. Review. |
|
HNPCC-associated small bowel cancer:
clinical and molecular characteristics. |
| Schulmann K, Brasch
FE, Kunstmann E, Engel C, Pagenstecher C, Vogelsang H, Kruger S,
Vogel T, Knaebel HP, Ruschoff J, Hahn SA, Knebel-Doeberitz MV,
Moeslein G, Meltzer SJ, Schackert HK, Tympner C, Mangold E,
Schmiegel W; The German HNPCC Consortium. |
| Gastroenterology. 2005
Mar;128(3):590-9. |
|
Prediction of lymph node metastasis
with use of artificial neural networks based on gene expression
profiles in esophageal squamous cell carcinoma. |
|
Kan T, Shimada Y, Sato F, Ito T, Kondo K, Watanabe G, Maeda M,
Yamasaki S, Meltzer SJ, Imamura M. |
|
Ann Surg Oncol. 2004 Dec;11(12):1070-8. Epub 2004 Nov 15. |
|
Spermine oxidation induced by
Helicobacter pylori results in apoptosis and DNA damage:
implications for gastric carcinogenesis. |
| Xu H,
Chaturvedi R, Cheng Y, Bussiere FI, Asim M, Yao MD, Potosky D,
Meltzer SJ, Rhee JG, Kim SS, Moss SF, Hacker A, Wang Y, Casero
RA Jr, Wilson KT. |
|
Cancer Res.
2004 Dec 1;64(23):8521-5. |
|
Activin type II receptor restoration
in ACVR2-deficient colon cancer cells induces transforming
growth factor-beta response pathway genes. |
| Deacu E, Mori
Y, Sato F, Yin J, Olaru A, Sterian A, Xu Y, Wang S, Schulmann K,
Berki A, Kan T, Abraham JM, Meltzer SJ. |
| Cancer Res.
2004 Nov 1;64(21):7690-6. |
|
Esophagin and proliferating cell
nuclear antigen (PCNA) are biomarkers of human esophageal
neoplastic progression. |
| Kimos MC,
Wang S, Borkowski A, Yang GY, Yang CS, Perry K, Olaru A, Deacu
E, Sterian A, Cottrell J, Papadimitriou J, Sisodia L, Selaru FM,
Mori Y, Xu Y, Yin J, Abraham JM, Meltzer SJ. |
|
Int J Cancer. 2004 Sep 1;111(3):415-7. |
|
Transcriptional responses of
intestinal epithelial cells to infection with Vibrio cholerae. |
|
Stokes NR, Zhou X, Meltzer SJ, Kaper JB. |
| Infect Immun. 2004
Jul;72(7):4240-8. |
|
A multigene expression panel for the
molecular diagnosis of Barrett's esophagus and Barrett's
adenocarcinoma of the esophagus. |
|
Brabender J, Marjoram P, Salonga D, Metzger R, Schneider PM,
Park JM, Schneider S, Holscher AH, Yin J, Meltzer SJ, Danenberg
KD, Danenberg PV, Lord RV. |
| Oncogene. 2004 Jun
10;23(27):4780-8. |
|
Identification of genes uniquely
involved in frequent microsatellite instability colon
carcinogenesis by expression profiling combined with epigenetic
scanning. |
|
Mori Y, Yin J, Sato F, Sterian A, Simms LA, Selaru FM, Schulmann
K, Xu Y, Olaru A, Wang S, Deacu E, Abraham JM, Young J, Leggett
BA, Meltzer SJ. |
| Cancer Res. 2004 Apr
1;64(7):2434-8. |
|
An unsupervised approach to identify
molecular phenotypic components influencing breast cancer
features. |
| Selaru FM,
Yin J, Olaru A, Mori Y, Xu Y, Epstein SH, Sato F, Deacu E, Wang
S, Sterian A, Fulton A, Abraham JM, Shibata D, Baquet C, Stass
SA, Meltzer SJ. |
|
Cancer Res.
2004 Mar 1;64(5):1584-8. |
|
Promoter methylation regulates
cyclooxygenase expression in breast cancer. |
|
Ma X, Yang Q, Wilson KT, Kundu N, Meltzer SJ, Fulton AM. |
| Breast Cancer Res.
2004;6(4):R316-21. Epub 2004 Apr 26. |
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