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CURRICULUM VITAE

EMOGRAPHIC INFORMATION
    Current Appointments:
    Associate Professor, Department of Pharmacology
    Johns Hopkins University School of Medicine, Baltimore, MD 21205
    Investigator, Center for High-throughput Biology
    Johns Hopkins University School of Medicine, Baltimore, MD 21205
    Positions:
    1990-1993
Research Assistant, Institute of Genetics, Chinese Academy of Sciences (CAS)
    1994-1999
Ph.D. research with Ralph Dean, Department of Plant Pathology, Clemson University
    1999-2004
Post-doctoral Fellow with Michael Snyder, Dept. of Molecular, Cellular & Developmental Biology, Yale University
    2003-
Adjunct Faculty, Beijing Institute of Genomics and Bioinformatics, CAS
    2004-
Assistant Professor, Dept. of Pharmacology, Johns Hopkins University School of Medicine
    2004-
Investigator, Center for High-Throughput Biology, Johns Hopkins University School of Medicine
    2005-
Assistant Professor, Oncology Research Center, Johns Hopkins University School of Medicine
    2010-
Associate Professor, Oncology Research Center, Johns Hopkins University School of Medicine
 
    Other Experience and Professional Memberships
    1995-1999
Member, American Pathopathology Society
    2001-2004
Consultant, Protometrix, Inc.
    Personal Data:
    333 Broadway Research Building
    733 N. Broadway
    Baltimore, MD 21205
    Tel: (410) 502-0878
    FAX: (410) 502-1872
 
    Education And Training (in chronological order):
     
Degrees/Year Institution Discipline chemistry
  • Undergraduate
BS/1990 Peking University Chemistry
  • Doctoral/graduate
PhD/1999 Clemson University Genetics
  • Postdoctoral
99-04 Yale University Proteomics
 
    Professional Experience (in chronological order):
    Dates
Positions Institutions chemistry
  • 09/90-12/93
Research Assistant Institute of Genetics, CAS
  • 01/94-02/99
PhD/1999 Ph.D. Candidate Clemson University
  • 03/99-02/04
Postdoctoral Fellow4 Yale University
  • 02/04-present
Assistant Professor Johns Hopkins University School of Medicine
RESEARCH ACTIVITIES
    Inventions, Patents, Copyrights (pending, awarded):
    Date
Title
    2001
Global analysis of protein activities using proteome chips.
    2001
Protein chips for high-throughput screening of protein activity.
    2005
SARS diagnostics using a coronavirus protein chip.
    2006
A novel approach to peptide/protein chip fabrication.
    2006
Fabrication and application of a prokaryotic proteome chip.
    Extramural Sponsorship:
  • Grants
    RFA RM-04-005
09/01/04-08/31/09
    NIH/TCNP
    Networks and Pathways of Lysine Modification
    Role: Co-Investigator
 
    USDA
01/15/06 每 01/14/09
    Characterization of the Transcriptional Circuitry Regulating Pathogenecity of the Rice Blast Fungus.
    Role: Co-Investigator
 
    NIH Lymphoma Spore
01/01/06 每 06/30/06
    Role: Co-Investigator
 
    R01 AI071340-01
03/01/06 每 08/31/07
    NIH
    Assays for Influenza Therapeutics: Project Bioshield
    Role: Co-Investigator
 
    R21 AI070740
07/01/06 每 06/30/08
    NIH/NIAID
    Structural Protein Networks (※Interactome§) in Herpesviruses
    Role: Principal Investigator
 
    R01 GM076102 (Zhu, PI)
07/01/06 每 06/30/11
    NIH/NIGMS
    DNA-Binding Activity of Human Transcription Factors
    Role: Principal Investigator
 
  • Contracts
EDUCATIONAL ACTIVITIES
  • Teaching:
    Protein Bioinformatics
    Pharmacology Tutorials
    Pharmacology Journal Club
    Graduate Pharmacology
  • Mentoring:
    Mr. Jian Zhu (graduate student)
    Ms. Lauren Vo (graduate student)
    Mr. Jun Kyu Rhee (graduate student)
    Ms. Crystal Woodard (graduate student)
    Ms. Nia White (graduate student)
    Dr. Sheng-ce Tao (postdoctoral fellow)
    Dr. Yuxin Wang (postdoctoral fellow)
    Dr. Chien-sheng Chen (postdoctoral fellow)
    Dr. Xiaofei He (postdoctoral fellow)
    Dr. Shaohui Hu (postdoctoral fellow)
    Dr. Heel-Soel Rho (postdoctoral fellow)
    Dr. Jin-ying Lu (postdoctoral fellow)
  • Editorial Activities:
CLINICAL ACTIVITIES(N/A)
 
RECOGNITION
    Awards, Honors:
    Postdoctoral fellowship, 2000-2004, Damon Runyon Cancer Research Foundation
    Chair*s Award, June 2000, the Gordon Research Conference
    Chair*s Award, July 1998, the Gordon Research Conference
    Member of Gamma Sigma Delta, 1994-1999, the Honor Society of Agriculture
 
    Invited Talks, Panels:
  1. Probing protein functions using protein chips. Mid Atlantic Bio. Washington, D.C. October 10, 2006

  2. Probing protein functions using protein chips. Industrial Microbial and Biotechnology. Baltimore, MD. August 2, 2006.

  3. Application of functional protein chips. SCBA Conference. San Francisco, Jul 19, 2006

  4. A novel approach to fabricate protein chips. 2006 Yeast Genetics Conference, Princeton, NJ. July 2006.

  5. Application of functional protein chips. Invited seminar. University of Iowa. Jul. 13, 2006

  6. Current progresses in yeast genomics and proteomics. Invited seminar, UAB, Barcelona, Spain. April 2006.

  7. Methods for analytical and functional protein chips. US HUPO Short Course. Boston, MA. Mar. 12, 2006

  8. Application of functional protein chips. Gordon Conference, Reversible association in structural & molecular biology. Ventura, CA. Jan 15-20, 2006

  9. Application of functional protein chips. 2006 CHI Pep Talk. San Diego, CA. Jan 12-13, 2006

  10. Protein chip fabrication and application. Invited seminar, University of British Columbia, Vancouver, Canada. Nov 17, 2005

  11. Probing protein functionality using protein chips. Invited seminar, Chinese Academy of Agricultural Sciences, Beijing, China. Dec. 20, 2005

  12. Applications of functional protein chips. November 2004, Emory University, Atlanta, GA.

  13. Applications of functional protein microarrays. September 2004, IBC*s Chips to Hits 2004, Boston, MA.

  14. Global analysis of protein activities using proteome chips. November 2002, Biochip Technologies 2002, Beijing, China.

  15. Global analysis of protein activities using proteome chips. February 2002, Seminar at North Carolina State University, Raleigh, NC.

  16. Global analysis of protein activities using proteome chips. March 2002, IBC*s Enzyme Technologies, San Francisco, CA.

  17. Global analysis of protein activities using proteome chips. March 2002, IBC*s Emerging Microarray Technologies, San Diego, CA.

  18. Global analysis of protein activities using proteome chips. October 2001, the Chips to Hits Conference, San Diego, CA.

  19. Global analysis of protein activities using proteome chips. September 2001, Microarray Technology Summit, Princeton, NJ.

  20. Global analysis of protein activities using proteome chips. September 2001, CHI Nanotechnology Conference, Columbus, OH.

  21. Analysis of yeast protein kinases using protein chips. June 2001, the CFBS Annual Meeting, Ottawa, Canada.

  22. Analysis of yeast protein kinases using protein chips. March 2001, IBC's Protein Microarray Technology Conference, San Diego, CA.

  23. Analysis of yeast protein kinases using protein chips. July 2000, Yeast Genetics & Molecular Biology Meeting, Seattle, WA.

  24. Localization and expression profiling of genes expressed during appressorium formation on chromosome 7 in Magnaporthe grisea. March 1999, 20th Fungal Genetic Conference, Asilomar, CA.

  25. Physical map construction of chromosome 7 in the rice blast fungus, Magnaporthe grisea. July 1998, the 49th International Genetics Conference, Beijing, China.

  26. BAC library and Physical map construction of chromosome 7 in the rice blast fungus, Magnaporthe grisea. July 1998, 10th Xiangshan Scientific Symposium, Beijing, China.

  27. A physical map and gene expression profile of M. grisea chromosome 7. November 1998, Annual Meeting of American Phytopathology Society, Las Vegas, NV.

  28. A large-insert (130 kbp) bacterial artificial chromosome library of the rice blast fungus Magnaporthe grisea: genome analysis, contig assembly, and gene cloning. August 1997, Annual Meeting of American Phytopathology Society, Rochester, NY.

Contact Information:
Heng Zhu
E-mail: hzhu4@jhmi.edu
Phone: (410) 502-0878
FAX: (410) 502-1872