Original Research Publications
Daniel Linzer, Se-Jin Lee, Linda Ogren, Frank Talamantes, and Daniel
Nathans (1985) Identification of proliferin mRNA and protein in mouse
placenta. Proc.
Natl. Acad. Sci., USA 82:4356-4359. [PDF
reprint]
Se-Jin Lee and Daniel Nathans (1987) Secretion of proliferin. Endocrinology 120:208-213.
[PDF reprint]
Se-Jin Lee and Daniel Nathans (1988) Proliferin secreted by cultured
cells binds to mannose-6-phosphate receptors. J. Biol. Chem. 263:3521-3527.
[PDF reprint]
Se-Jin Lee, Frank Talamantes, Elizabeth Wilder, Daniel Linzer, and
Daniel Nathans (1988) Trophoblastic giant cells of the mouse
placenta as the site of proliferin synthesis. Endocrinology 122:1761-1768.
[PDF reprint]
Se-Jin Lee (1990) Expression of HSP86 in male germ cells. Mol.
Cell. Biol. 10:3239-3242. [PDF
reprint]
Se-Jin Lee (1990) Identification of a novel member (GDF-1) of the
transforming growth factor-ß superfamily. Mol. Endocrinol. 4:1034-1040.
[PDF reprint]
Se-Jin Lee (1991) Expression of growth/differentiation factor-1
in the nervous system: Conservation of a bi-cistronic structure. Proc.
Natl. Acad. Sci., USA 88:4250-4254. [PDF
reprint]
Alexandra C. McPherron and Se-Jin Lee (1993) GDF-3 and GDF-9: Two
new members of the transforming growth factor-ß superfamily containing
a novel pattern of cysteines. J. Biol. Chem. 268:3444-3449. [PDF
reprint]
Elaine E. Storm, Thanh V. Huynh, Neal G. Copeland, Nancy A. Jenkins, David
M. Kingsley, and Se-Jin Lee (1994) Limb alterations in brachypodism mice
due to mutations in a new member of the TGF-ß superfamily. Nature 368:639-643.
[PDF reprint]
Sharon A. McGrath, Aurora F. Esquela, and Se-Jin Lee (1995) Oocyte-specific
expression of growth/differentiation factor-9. Mol. Endocrinol. 9:131-136.
[PDF reprint]
Noreen S. Cunningham, Nancy A. Jenkins, Debra J. Gilbert, Neal G. Copeland,
A. Hari Reddi, and Se-Jin Lee (1995) Growth/Differentiation Factor-10:
A new member of the transforming growth factor-ß superfamily related
to bone morphogenetic protein-3. Growth Factors 12:99-109. [PDF
reprint]
Alexandra C. McPherron, Ann M. Lawler, and Se-Jin Lee (1997) Regulation
of skeletal muscle mass in mice by a new TGF-ß superfamily member. Nature 387:83-90.
[PDF reprint]
Aurora F. Esquela, Teresa A. Zimmers, Leonidas G. Koniaris, James V. Sitzmann,
and Se-Jin Lee (1997) Transient down-regulation of inhibin-ßC
expression following partial hepatectomy. Biochem. Biophys. Res. Comm. 235:553-556.
[PDF reprint]
Alexandra C. McPherron and Se-Jin Lee (1997) Doubling muscling in
cattle due to mutations in the myostatin gene. Proc. Natl. Acad. Sci.,
USA 94:12457-12461. [PDF
reprint]
Alexandra C. McPherron, Ann M. Lawler, and Se-Jin Lee (1999) Regulation
of anterior/posterior patterning of the axial skeleton by growth/differentiation
factor-11. Nature Genet. 22:260-264. [PDF
reprint]
Renbin Zhao, Ann M. Lawler, and Se-Jin Lee (1999) Characterization
of GDF-10 expression patterns and null mice. Dev. Biol. 212:68-79.
[PDF reprint]
Christopher T. Rankin, Tracie Bunton, Ann M. Lawler, and Se-Jin Lee (2000)
Regulation of left-right patterning in mice by growth/differentiation
factor-1. Nature
Genet. 24:262-265. [PDF
reprint]
Edward C. Hsiao, Leonidas G. Koniaris, Teresa A. Zimmers-Koniaris, Suzanne
M. Sebald, Thanh Huynh, and Se-Jin Lee (2000) Characterization of
growth/differentiation factor-15 (Gdf15): a TGF-ß superfamily
member induced following liver injury. Mol. Cell. Biol. 20:3742-3751.
[PDF reprint]
Se-Jin Lee and Alexandra C. McPherron (2001) Regulation of myostatin
activity and muscle growth. Proc. Natl. Acad. Sci., USA 98:9306-9311.
[PDF reprint]
Alexandra C. McPherron and Se-Jin Lee (2002) Suppression of body
fat accumulation in myostatin-deficient mice. J. Clin. Invest. 109:595-601.
[PDF reprint]
Teresa A. Zimmers, Monique V. Davies, Leonidas G. Koniaris, Paul Haynes,
Aurora F. Esquela, Kathy N. Tomkinson, Alexandra C. McPherron,
Neil M. Wolfman, and Se-Jin Lee (2002) Induction of cachexia in mice
by systemically administered myostatin. Science 296:1486-1488.
Kathryn R. Wagner, Alexandra C. McPherron, Nicole Winik, and Se-Jin
Lee (2002) Loss of myostatin attenuates severity of muscular dystrophy
in mdx mice. Ann. Neurol. 52:832-836.
Aurora F. Esquela and Se-Jin Lee (2003) Regulation of metanephric
kidney development by growth/differentiation factor 11. Dev. Biol. 257:356-370.
Neil M. Wolfman, Alexandra C. McPherron, William N, Pappano, Monique V.
Davies, Kening Song, Kathleen N. Tomkinson, Jill F. Wright,
Liz Zhao, Suzanne M. Sebald, Daniel S. Greenspan, and Se-Jin Lee (2003)
Activation of latent myostatin by the BMP-1/tolloid family
of metolloproteinases. Proc.
Natl. Acad. Sci., USA 100:15842-15846. [PDF
reprint]
Markus Schuelke, Kathryn R. Wagner, Leslie Stolz, Christoph Hubner, Thomas
Riebel, Wolfgang Komen, Thomas Braun, James F. Tobin, and Se-Jin Lee (2004)
Gross muscle hypertrophy in a child associated with a myostatin
(GDF-8) mutation. New Engl. J. Med. 350 :2682-2688. [PDF
reprint]
Se-Jin Lee, Lori A. Reed, Monique V. Davies, Stefan Girgenrath,
Mary E.P. Goad, Kathy N. Tomkinson, Jill F. Wright, Christopher Barker,
Gregory Ehrmantraut, James Holmstrom, Betty Trowell, Barry Gertz, Man-Shiow
Jiang, Suzanne M. Sebald, Martin Matzuk, En Li, Li-fang Liang, Edwin Quattlebaum,
Ronald L. Stotish, and Neil M. Wolfman (2005) Regulation of muscle growth
by multiple ligands signaling through activin type II receptors. Proc.
Natl. Acad. Sci., USA 102:18117-18122. [PDF
reprint]
Se-Jin Lee (2007) Quadrupling muscle mass in mice by targeting TGF-ß signaling pathways. PLoS ONE 2(8):e789. doi:10.1371/journal.pone.0000789. [PDF
reprint]
Se-Jin Lee (2008) Genetic analysis of the role of proteolysis in the activation of latent myostatin. PLoS ONE 3(8):e1628. doi:10.1371/journal.pone.0001628. [PDF
reprint]
Alexandra C. McPherron, Thanh V. Huynh, and Se-Jin Lee (2009) Redundancy of myostatin and growth/differentiation factor 11 function. BMC Dev. Biol. 9:24. doi:10.1186/1471-213X-9-24. [PMID: 19298661] [PDF
reprint]
Yuichi Oshima, Noriyuki Ouchi, Masayuki Shimano, David R. Pimentel, Kyriakos N. Papanicolaou, Kalyani D. Panse, Kunihiro Tsuchida, Enrique Lara-Pezzi, Se-Jin Lee, and Kenneth Walsh (2009) Activin A and follistatin-like 3 determine the susceptibility of heart to ischemic injury. Circulation 120:1606-1615. [PMID: 19805648] [PDF
reprint]
Kevin J. Morine, Lawrence T. Bish, Joshua T. Selsby, Jeffrey A. Gazzara, Klara Pendrak, Meg M. Sleeper, Elisabeth R. Barton, Se-Jin Lee, and H. L. Sweeney (2010) Activin IIB receptor blockade attenuates dystrophic pathology in a mouse model of Duchenne muscular dystrophy. Muscle Nerve 42:722-730. [PMID: 20730876]
Se-Jin Lee, Yun-Sil Lee, Teresa A. Zimmers, Arshia Soleimani, Martin M. Matzuk, Kunihiro Tsuchida, Ronald D. Cohn, and Elisabeth R. Barton (2010) Regulation of muscle mass by follistatin and activins. Mol. Endocrinol. 24:1998-2008. [PMID: 20810712] [PDf reprint]
Young Jae Lee, Alexandra McPherron, Susan Choe, Yasuo Sakai, Roshantha A. Chandraratna, Se-Jin Lee, and S. Paul Oh (2010) Growth differentiation factor 11 signaling controls retinoic acid activity for axial vertebral development. Dev. Biol. 347:195-203. [PMID: 20801112] [PDF reprint]
Saskia C.A. de Jager, Beatriz Bermúdez, Ilze Bot, Rory R. Koenen, Martine Bot, Annemieke Kavelaars, Vivian de Waard, Cobi J. Heijnen, Francisco J.G. Muriana, Christian Weber, Theo J.C. van Berkel, Johan Kuiper, Se-Jin Lee, Rocio Abia, and Erik A.L. Biessen (2011) Growth differentiation 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis. J. Exp. Med. 208:217-225. [PMID: 21242297]
Masayuki Shimano, Noriyuki Ouchi, Kazuto Nakamura, Yuichi Oshima, Akiko Higuchi, David R. Pimentel, Kalyani D. Panse, Enrique Lara-Pezzi, Se-Jin Lee, Flora Sam, and Kenneth Walsh (2011) Cardiac myocyte-specific ablation of follistatin-like 3 attenuates stress-induced myocardial hypertrophy. J. Biol. Chem. 286:9840-9848. [PMID: 21245136]
Nicolas Ricard, Delphine Ciais, Sandrine Levet, Mariela Subileau, Christine Mallet, Teresa A. Zimmers, Se-Jin Lee, Marie Bidart, Jean-Jacques Feige, and Sabine Bailly (2012) BMP9 and BMP10 are critical for postnatal retinal vascular remodeling. Blood 119:6162-6171. [PMID: 22566602]
Yi Liu-Chittenden, Bo Huang, Joong Sup Shim, Qian Chen, Se-Jin Lee, Robert A. Anders, Jun O. Liu, and Duojia Pan (2012) Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes Dev. 26:1300-1305. [PMID: 22677547]
Se-Jin Lee, Thanh V. Huynh, Yun-Sil Lee, Suzanne M. Sebald, Sarah Wilcox-Adelman, Naoki Iwamori, Christoph Lepper, Martin M. Matzuk, and Chen-Ming Fan (2012) Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway. Proc. Natl. Acad. Sci., USA 109:E2353-E2360. doi:10.1073/pnas.1206410109. [PMID: 22869749] [PDF reprint]
Yang A. Roby, Michael A. Bushey, Li E. Cheng, Heather M. Kulaga, Se-Jin Lee, and Randall R. Reed (2012) Zfp423/OAZ mutation reveals the importance of Olf/EBF transcription activity in olfactory neuronal maturation. J. Neurosci. 32:13679-13688a. [PMID: 23035080]
Raouia Fakhfakh, Se-Jin Lee, and Jacques P. Tremblay (2012) Administration of a soluble activin type IIB receptor promotes the transplantation of human myoblasts in dystrophic mice. Cell Transplant., in press [PMID: 22449443]
Sandrine Levet, Delphine Ciais, Galina Merdzhanova, Christine Mallet, Teresa A. Zimmers, Se-Jin Lee, Fabrice P. Navarro, Isabelle Texier, Jean-Jacques Feige, Sabine Bailly, and Daniel Vittet (2013) Bone Morphogenetic Protein 9 (BMP9) controls lymphatic vessel maturation and valve formation. Blood, 122:598-607.
Yun-Sil Lee and Se-Jin Lee (2013) Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2. Proc. Natl. Acad. Sci., USA 110:E3713-22. doi: 10.1073/pnas.1309907110. [PDF reprint]
Review Articles and Commentaries
Alexandra C. McPherron and Se-Jin Lee (1996) The transforming growth
factor-ß superfamily. In Growth Factors and Cytokines in Health
and Disease, vol. 1B. D. LeRoith and C. Bondy, eds. JAI Press, Inc., Greenwich,
CT, pp. 357-393.
Se-Jin Lee and Alexandra C. McPherron (1999) Myostatin and the control
of skeletal muscle mass. Curr. Opin. Genet. Dev. 9:604-607. [PDF
reprint]
Se-Jin Lee (2004) Regulation of muscle mass by myostatin. Ann.
Rev. Cell Dev. Biol. 20:61-86
Se-Jin Lee (2007) Sprinting without myostatin: a genetic determinant of athletic prowess. Trends Genet. 23:475-477.
Se-Jin Lee (2010) Speed and endurance: you can have it all. J. Appl. Physiol. 109:621-622. [PMID: 20538843] [PDF reprint]
Se-Jin Lee (2010) Extracellular regulation of myostatin: a molecular rheostat for muscle mass. Immun., Endoc. & Metab. Agents in Med. Chem., 10:183-194. [PDF
reprint]
Se-Jin Lee and David J. Glass (2011) Treating cancer cachexia to treat cancer. Skeletal Muscle, 1:2. [PDF
reprint]
Se-Jin Lee (2012) Myostatin: regulation, function, and therapeutic applications. In Joseph A. Hill and Eric N. Olson (Eds.), Muscle: Fundamental Biology and Mechanisms of Disease (pp. 1077-1084). Academic Press. |