Course Schedule—Spring 2008

Biology

Note: Text highlighted in red indicates that a change has been made to the course listing. The red text indicates the current, updated information.

BIOLOGY

020.102 (N)

FRESHMEN SEMINAR:  WE ARE WHAT WE EAT (1) Lee Freshmen only   Limit 25 Why do we eat? What do we eat? How do we eat? What happens to what we eat? Biochemical and nutritional aspects of food we take will be discussed.

 

M 1:30-2:20

020.103 (N)

FRESHMEN SEMINAR:  INTRODUCTION TO BIOMEDICAL RESEARCH (1.5)  Roseman Freshmen only    Limit 14 16

Sec. 01

M 4:30-5:45pm

020.125 (H,N)

BIOLOGY IN FILM (1) Hedgecock Limit 300 S/U grading only This course will feature weekly presentations of highly acclaimed, Hollywood films. Each film will be hosted by a different member of the Biology faculty who will provide an introduction and discussion of the film. Film topics include early discoveries in the biomedical arena, genetic and infectious diseases, and the potential consequences of human genetic engineering. Students will be expected to attend all classes and complete out a questionnaire based on each film.

Sec. 01

Th 7-9:30pm

020.152 (N)

GENERAL BIOLOGY II (4) McCarty/Pearlman/Shingles Prereq: 020.151   Limit 320 This course builds on the concepts presented and discussed in General Biology I.  The primary foci of this course will be on the diversity of life and on the anatomy, physiology, and evolution of plants and animals. There will be a special emphasis on human biology. The workshops that were introduced in 020.151 General Biology I will include the use of simulation software, a critique of the primary literature, and an exploration of current trends in medicine.
Cross-listed with Behavioral Biology

Sec. 01

Wrkshp.

MWF 12-12:50

T 12-12:50

020.154 (N)

GENERAL BIOLOGY LAB II (1) Pearlman  Coreq: 020.152 This course reinforces the topics covered in 020.152.  Laboratory exercises explore subjects ranging from evolution to anatomy and physiology. Students participate in a project using molecular biology techniques to determine whether specific foods are made from genetically engineered plants.

Cross-listed with Behavioral Biology

Lec.
Sec. 01
02
03
04
05

Th 12-12:50
M 1:30-4:20
T 1:30-4:20
W 1:30-4:20
Th 1:30-4:20
F 1:30-4:20

020.162 (N)

BIOLOGY WORKSHOP II (1) Pearlman  Limit: 60   Prereq: A score of 4 or 5 on the AP Biology exam The Biology Workshop covers applications and current trends in biology through guest lectures from researchers and hands-on computer programs.  Credit will be awarded for either 020.152 or 020.162, but not both.

Sec. 01

T 12-12:50

020.306 (N)

CELL BIOLOGY (4) Moudrianakis  Limit 320 340 Prereq: 020.305 How the molecules of living systems are organized into organelles, cells, tissues, and organisms will be explored, as well as how the activities of all of these are orchestrated and regulated to produce “life”—a phenomenon greater than the sum of its parts. Considerable emphasis is placed on experimental approaches to answering these questions.  Topics covered include biological membranes, cytoskeletal elements, cell locomotion, membrane and protein traffic, the nucleus, second messengers, signal transduction, cell growth, the cell cycle, the extracellular matrix, cell contacts and adhesion, intercellular communication, epithelial structure and function, and the cell biology of early development and organ function.

Sec. 01

MWF 12-1:15

020.312 (N)

INTRODUCTION TO THE HUMAN BRAIN (3) Hedgecock   Limit 100 60 This course explores the outstanding problem of biology: how knowledge is represented in the brain.  Relating insights from cognitive psychology and systems neuroscience with formal theories of learning and memory, topics include: (1) anatomical and functional relations of cerebral cortex, basal ganglia, limbic system, thalamus, cerebellum and spinal cord; (2) cortical anatomy and physiology including laminar/columnar organization, intrinsic cortical circuit, hierarchies of cortical areas; (3) activity-dependent synaptic mechanisms; (4) functional brain imaging; (5) logicist and connectist theories of cognition; and (6) relation of mental representations and natural language. Co-listed as 020.612

Sec. 01

TTh 1:30-2:45

020.316 (N)

CELL BIOLOGY LAB (2) Horner  Limit 60 per section   Prereq: 020.305   Coreq. 020.306 First lab section meeting 1/28/08  This course will reinforce the topics presented in 020.306 Cell Biology through laboratory exercises which use visible and fluorescence microscopy to study chromosomes, cell organelles, cell surface receptors, contractile proteins, and microfilaments.

Sec. 04 added 10/30/07
Sec. 05 added 01/28/08

Lec.

Sec. 01

02

03

04


05

W 1:30-2:20

T 1:30-4:20

W 2:30-5:20

Th 1:30-4-20

F 1:30-4:20

M 1:30-4:20

020.321 (N)

MEDICAL BIOCHEMISTRY (3) Wondisford   Limit 100 Prereq: Knowledge of cell biology and basic biochemistry is important and can be fulfilled by taking 020.305 and 020.306, or by permission of the intructor. This course will stress the importance of a strong background in biochemistry in those students interested in the study of medicine. Important biochemical pathways will be reviewed and highlighted using actual human metabolic diseases as case studies.
Course canceled 01/03/08

Sec. 01

TTh 9-10:15

020.325 (N)

INTRODUCTION TO THE PROTEIN WORLD (3) Privalov   Limit 25 Will be considered the chemical, physical, and biological aspects of proteins; their primary, secondary, tertiary, and quaternary structures; evolution of these structures and mechanisms of their formation and functioning.  

Sec. 01

TTh 10:30-11:45

020.326 (N)

INTRODUCTION TO GLYCOBIOLOGY (3) Lee   Prereq: 020.305   Limit 25 Carbohydrates are not for energy (e.g., starch) or structure (e.g., cellulose) only. Carbohydrates conjugated to proteins and lipids (Glycoconjugates) perform diverse and intricate biological reactions. More than 2/3 of all proteins in eukaryotes are glycosylated. Glycolipids are vital elements of cell membranes, especially in the nervous tissues. Many pathogens (e.g., influenza virus) utilizes glycoconjugates on human cells to invade. Structures and biological functions of glycoconjugates will be discussed in this course.
  

Sec. 01

MW 11-11:50

020.333 (N)

ADAPTATIONS OF PLANTS TO THEIR ENVIRONMENT (2) McCarty Limit 60  Prereq: 020.151-152 or AP Biology credit This course is an introduction to the ecological physiology of higher plants. Plants grow in the tropics and the tundra, in extremely dry or wet situations, and even in salt water. The adaptations of plants to their environments will be discussed.

Sec. 01

TTh 10:30-11:45

020.335 (N)

LANDMARKS IN BIOCHEMICAL RESEARCH (2) Roseman  Limit 31 35 60 16 Prereq: Grades of B or better in the following: Biology 020.305. 020.315, Chemistry 030.205    An advanced biochemistry course designed for upperclassmen. Emphasis will be on the origins of important biochemical concepts, and on the essential role of quantitative thinking in the experiments that led to these ideas. Original and current papers will be analyzed.

Sec. 01

W 3-5pm

020.347 (N)

AIDS (3) Schroer Limit 60  Prereq: 020.306 AIDS is the world’s deadliest infectious disease. This course will cover the biology of the infectious agent that causes AIDS, human immunodeficiency virus (HIV), the effects of HIV on the immune system, the search for an HIV vaccine, and the pharmacology of the anti-viral agents that are used to suppress HIV infection. Because HIV drugs cannot cure HIV-infected individuals, we will also study the long-term consequences of HIV infection including opportunistic infections and the HIV related cancers Kaposi’s sarcoma and lymphoma.
Cross-listed with Public Health

Sec. 01

TTh 1:30-2:50 

020.363 (N)

DEVELOPMENTAL BIOLOGY (3) Van Doren/Norris Limit 140 Prereq: 020.305-306, 020.330 Development of invertebrates, vertebrates and plants. The course will emphasize the experimental bases for the fundamental concepts of development.

Sec. 01

MWF 10-10:50

020.367 (N)

PRIMATE BEHAVIOR AND ECOLOGY (3) Teaford Limit 25 30  A close look at our closest living realtives. Topics to be discussed: the past and present distributions of primates; primate taxonomy, feeding and diet, reproduction, social organization, communication, community relationships, and conservation.

Sec. 01

TTh 3-4:15 

020.373

DEVELOPMENTAL BIOLOGY LABORATORY  (2) Kondo Coreq: 020.363  Limit 20 per section This laboratory explores the development of organisms, and students in each section will therefore be required to return to lab on succeeding days to observe and record the results of their experiments.   

Sec. 01

02

03

T 1:30-5:20

W 1:30-5:20

Th 1:30-5:20

020.402 (N)

SEMINAR:  CURRENT PROGRESS IN CELLULAR AND MOLECULAR BIOLOGY AND BIOPHYSICS (3) Norris Horner  Limit 15  BA/MS candidates only    This a weekly seminar designed for graduate students enrolled in the BA/MS and Ph.D. programs.  The seminar involves student presentations of research and discussions on topics of current interest in the field.

Sec. 01

W 6:50-9:30pm 12-2:30

020.420 (N)

BUILD-A-GENOME (4) Boeke/Bader/Ostermeier  Limit 16 Perm Req'd Must understand fundamentals of DNA structure, DNA electrophoresis and analysis, Polymerase Chain Reaction (PCR) and must be either a) Experienced with molecular biology lab work or b) Adept at programming with a biological twist. In this combination lecture/laboratory "Synthetic Biology" course students will learn how to make DNA building blocks used in an int'l. project to build the world's first synthetic eukaryotic genome, Saccharomyces cerevisiae v. 2.0. Please study the wiki www.syntheticyeast.org for more details about the project. Following a biotechnology boot-camp, students will have 24/7 access to computational and wet-lab resources and will be expected to spend 15-20 hours per week on this course. Advanced students will be expected to contribute to the computational and biotech infrastructure. Co-listed with 580.420 & 540.420 Successful completion of this course provides 3 credit hours toward the supervised research requirement for Molecular and Cellular Biology majors, or 2 credit hours toward the upper level elective requirement for Biology or Molecular and Cellular Biology majors. Course added 12/06/07

Sec. 01

MWF 5-6:30pm

020.442

MENTORING IN BIOLOGY (1) Pearlman/Shingles  Limit 19 S/U only   Perm. Req’d.   To become a mentor, students must have successfully completed 020.151/152, must apply using the form on the Biology Dept. Website, and must be accepted by the instructors.

Sec. 01

TBA

020.451

BUILD-A-GENOME MENTOR (4) Boeke  Limit 4 Perm Req'd Prereq: 020.420 In addition to producing and sequencing DNA segments like regular B-a-G students, mentors will help prepare and distribute reagents, and maintain a Moddle site to track student reagent use and productivity. Mentors will also be expected to mentor specific students who are learning new techniques for the first time, contribute to the computational and biotech infrastructure associated with Build-a-Genome, and pursue at least one independent research project. Co-listed with 580.492 Successful completion of this course provides 3 credit hours toward the supervised research requirement for Molecular and Cellular Biology majors. Course added 12/06/07

Sec. 01

MWF 5-6:30pm

080.310 (N) COMMUNICATION BETWEEN CELLS: THE SYNAPSE AS A MODEL SYSTEM (CM) (3) Kirkwood Limit 30 Prereq: 020.305-306 and 080.301 See Neuroscience for full description Cross-listed with Neuroscience Course added 11/02/07

Sec. 01

WF 3-4:15 

020.502

INTRODUCTION INDEPENDENT STUDY Horner/Cunningham  Freshmen/Sophomores Only

020.504

INTRODUCTION TO RESEARCH Staff

020.506

INTERNSHIP IN BIOLOGY Staff

020.512

INDEPENDENT STUDY Staff 
Juniors and Seniors only

020.514

RESEARCH PROBLEMS Staff  Juniors and Seniors only

020.553

MENTORED RESEARCH PROGRAM IN CELLULAR & MOLECULAR BIOLOGY (9) Staff
BA/MS candidates only

TBA

020.612

INTRODUCTION TO THE HUMAN BRAIN Hedgecock    Limit 20 This course explores the outstanding problem of biology; how knowledge is represented in the brain. Relating insights from cognitive psychology and systems neuroscience with formal theories of learning and memory, topics include (1) anatomical and functional relations of cerebral cortex, basal ganglia, limbic system, thalamus, cerebellum, and spinal cord; (2) cortical anatomy and physiology including laminar/columnar organization, intrinsic cortical circuit, hierarchies of cortical areas; (3) activity-dependent synaptic mechanism; (4) functional brain imaging; (5) logicist and connectist theories of cognition; and (6) relation of mental representations and natural language.  Co-listed as 020.312

Sec. 01

TTh 1:30-2:45

020.613

BIOLOGY SCIENCE WRITING Huang   Limit 12 Perm. Req’d 
Graduate students only

Sec. 01

T 5:30-7:20pm

020.615

COMMUNICATION BETWEEN CELLS: THE SYNAPSE AS A MODEL SYSTEM Kikwood   Limit 25 Prereq: 020.305-306 & 080.301 Same as 080.310 Course added 01/15/08

Sec. 01

WF 3-4:15

020.629

HUMAN CANCER BIOLOGY AND TREATMENTS Huang  Limit 30 12 Seniors by permission only. This research oriented course is open to all graduate students. Lectures include updates of recent findings in carcinogenesis, proliferation, apoptosis, and novel chemotherapeutic targets.

Sec. 01

M 4-6pm

020.637

GENOMES AND DEVELOPMENT
Van Doren/Bortvin/Spradling/Halpern    Limit 25 This course covers gametogenesis, embryogenesis, post-embryonic development, genetic analysis, developmental genetics, model developmental systems, and cell determination.

Sec. 01

TTh 9-10:15

020.638

REGULATION OF THE CELL CYCLE Hoyt   Limit 12

Sec. 01

W 10-12

020.674

GRADUATE BIOPHYSICAL CHEMISTRY Woodson/ Brand/ Hill/ Bowman   Prereq: 020.305-306   Limit 40   This course provides an overview of protein and nucleic acid structure, fundamentals of thermodynamics and kinetics, ligand binding, folding and stability of macromolecules, and the physical principles of fluorescence spectroscopy, NMR spectroscopy, and X-ray diffraction.   Co-listed as 250.644

Sec. 01

M 2-3:20, TTh 10:30-11:45

020.679

ADVANCED BIOLOGICAL ELECTRON MICROSCOPY McCaffery   Perm. Req’d. Limit 6 per section This course builds upon the basic skills and knowledge students acquired in020.395 and 020.397. The course will emphasize the integration and use of various light and electron microscopy techniques and their application to various biomedical research related questions; with students participating in the design, implementation, and analysis of their own experiments or experiments pertaining to ongoing research in the Center. The course will be comprised of a practical "hands-on" component but will also include applied theory as students will read, analyze and discuss current journal articles.

Lec.

Sec. 01

02

MWF 1:30-2:20

T 9-11:50

Th 9-11:50

020.683

THERMODYNAMICS OF BINDING AND CONFORMATIONAL EQUILIBRIUM IN PROTEINS Freire Limit 25 During the course of biological function, proteins interact with other macromolecules and with small molecules.  These binding events trigger specific signals that result in the activation or inhibition of specific pathways in the cell.  Molecular interactions require the ability of the interacting partners to recognize each other, for which precise three dimensional conformations are required.  Understanding the way in which molecules recognize each other provides a way to understand cell function and the molecular basis for the development of new medical strategies aimed at treating disease.  This course will provide an in depth coverage of the fundamental thermodynamic forces and mechanisms that control the conformational equilibrium and binding interactions of proteins. Course canceled 01/23/08

Sec. 01

TTh 1-1:50

020.739

SEMINAR: TOPICS IN BIOCHEMISTRY Bessman  Limit 12 "Topics in Biochemistry" deals with minireviews taken from the Journal of Biological Chemistry. Students select a topic of their choice from the "Compendium of Minireviews" for the current year, and present it before the class for discussion.  The course is open to graduate students and advanced undergraduates.

Sec. 01

Th 12:30-1:50

020.802

RESEARCH IN BIOLOGICAL PROBLEMS Staff
Biology Graduate students only

TBA

020.825

INTRODUCTION TO BIOLOGY RESEARCH Staff    Open to first year Biology graduate students only

TBA

020.826

INTRODUCTION TO BIOLOGY RESEARCH Staff    Open to first year Biology graduate students only

TBA

MEDICINE TUTORIALS

These School of Medicine courses are open only to selected junior and senior pre-medical students with the approval of their faculty advisor and Preprofessional Advising, Garland Hall - Third Floor. Interdivisional registration is required.

A separate list of the tutorials to be offered will be available at the Registrar's Office after classes begin. Do not list tutorial courses on your course list form. Registration for these courses is accomplished by submitting an approved "add" slip and interdivisional registration form to Preprofessional Advising, as soon as possible after classes begin, and in any event, not later than the fourth week of classes.

Please note: No area code credit is given toward degree for the Medicine tutorials and all tutorials are graded Satisfactory/Unsatisfactory.

 

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