BIOPHYSICS

250.131 (N)

TOPICS IN BIOPHYSICS RESEARCH (1) Fleming, K. Freshmen and Sophomores only
Discussion-oriented course in which the Biophysics faculty present seminars on their current work or contemporary areas of research in biophysics.

Sec. 01

M 6-7:15pm

250.332 (N)

X-RAY CRYSTALLOGRAPHY OF BIOLOGICAL MOLECULES (3) Lattman  Prereq: Elementary Physics & Calculus
Course emphasizes use of crystallography to determine atomic structure of biological macromolecules. Also covers basics such as lattices, space groups, and symmetry. A text will be used.

Sec. 01

ThF 9-10:15

250.345 (N)

CELLULAR AND MOLECULAR PHYSIOLOGY (3) Cone Prereq: 020.305   How cells and molecules function as parts of whole organisms. Topics include life cycles of molecules, cells and organisms, cellular and organismic circulatory systems, gas transport, sensory mechanisms, muscle and molecular motors, and virus host interactions.
Cross-listed with Biology and Neuroscience

Sec. 01

MTW 11

250.351 (N)

REPRODUCTIVE PHYSIOLOGY (2) Zirkin/Cone   Prereq: 020.305
Focuses on reproductive physiology and on the biochemical and molecular regulation of the female and male reproductive tracts. Topics include the hypothalamus and pituitary, peptide and steroid hormone action, epididymis and male accessory sex organs, female reproductive tract, menstrual cycle, ovulation and gamete transport, fertilization and fertility enhancement, sexually transmitted diseases, and male and female contraceptive methods. Introductory lectures on each topic followed by research-oriented lectures and readings from current literature. 
Cross-listed with Biology and Women, Gender, & Sexuality

Sec. 01

W 4-5:45pm

250.353 (N)

BIOMOLECULAR DYNAMICS & ENSEMBLES (3) Fleming, P.   Limit 15    Recommended Prereq: 020.305, 030.101
Biological macromolecules and molecular assemblies exist as ensembles of structures which vary considerably in overall conformation and/or configuration.  An understanding of biomolecule structural diversity and conformational flexibility is important for understanding cellular synthesis and function of biological macromolecules. This course examines the dynamic nature of proteins and how this dynamics affects the experimental determination of protein and membrane structure and function. It explores how dynamic systems are generated computationally and analyzed, especially with regard to how these analyses relate to experimental data on biological systems. Exercises in computer programming and structural biology software applications will be given. However, the focus of the course is not mathematical but biological.

Sec. 01

ThF 1-2:20

250.401 (N)

ADVANCED SEMINAR IN BIOPHYSICS (3) Garcia-Moreno
Focus is on structural and molecular virology.  Topics include structural and physical aspects of viruses, replication cycles, evolution and focused discussion on the structural basis of the life cycle of human pathogens such as the influenza virus and HIV.  Course shows integration between quantitative and physical biophysical approaches and contemporary biological questions.  020.305 Biochemistry and 250.372 Introduction to Biophysical Chemistry helpful. Course canceled 08/30/05

Sec. 01

T 3-5:20

250.519

INDEPENDENT STUDY

250.521

RESEARCH PROBLEMS

250.531

LABORATORY IN BIOPHYSICS
Permission from Faculty Sponsor   Introduction to Independent research in biophysics, with emphasis on basic laboratory techniques. Individual course of study to be arranged with faculty mentor.

250.601

BIOPHYSICS SEMINAR Cone Perm. Req'd.   Graduate students only
Students and invited speakers present current topics in the field.

Sec. 01

M 4

250.631

LABORATORY RESEARCH IN BIOPHYSICS Staff
Research training in biophysics.

Sec. 01

TBA

540.667

ENGINEERING MODELING AND ANALYSIS OF BIOLOGICAL SYSTEMS Paulaitis

Cross-listed with Biomedical Engineering,Chemical & Biomolecular Engineering, Civil Engineering, and Mechanical Engineering

Sec. 01

T 4, W 3-6pm

540.667

ENGINEERING MODELING AND ANALYSIS OF BIOLOGICAL SYSTEMS Paulaitis

Cross-listed with Biomedical Engineering, Biophysics, Civil Engineering, and Mechanical Engineering
Course added 09/02/05

Sec. 01

T 4-6pm, W 3-6pm

250.673

SEMI-ANNUAL THESIS Fleming, K.  Biophysics Graduate students only
Once each term, advanced graduate students make a 10-minute presentation of their thesis work to the departmental faculty. The presentation is followed by a half-hour discussion.

Sec. 01

TBA

250.683

INTRODUCTION TO UNIX PYTHON Rose   Two-week course, 9/12/05 – 9/21/05  Required for 250.685 Proteins and Nucleic Acids

Sec. 01

MTW 10:30-11:20

250.685

PROTEINS & NUCLEIC ACIDS Rose Prereq: 250.683   Course begins 9/26/05  Proteins as nature’s molecular robots, and DNA/RNA as the genetic material. Experimental and theoretical approaches to macromolecules, including modeling, simulating and visualizing three-dimensional structures.

Sec. 01

MTW 10:30-11:20

250.689

PHYSICAL CHEMISTRY OF BIOLOGICAL MACROMOLECULES Garcia-Moreno     Introduction to principles, methods, and approaches used in study of the energetics of proteins and nucleic acids, with emphasis in understanding the relationship between structure, energy, dynamics, and biological function. Topics include classical, chemical, and statistical thermodynamics, kinetics, theory of ligand binding, and conformational equilibria.    

Sec. 01

MW 9-10:15

250.693

BIOLOGICAL PRINCIPLES FOR PHYSICAL SCIENTISTS Garcia-Moreno / Barrick  Perm. Req'd. An introduction to modern biology at the cellular and subcellular level, focusing on molecular and cell biology and biochemistry. This course is meant for individuals with backgrounds in engineering and physical sciences with little or no previous exposure to biology or chemistry. The course is meant to provide a basic biological framework tohelp inform quantitative computational and physical studies on biological problems. Course added 08/25/05   

Sec. 01

TTh 9-10:15

250.801

DISSERTATION RESEARCH Fleming