CHEMICAL & BIOMOLECULAR ENGINEERING

540.202 (E)

INTRODUCTION TO CHEMICAL AND BIOLOGICAL PROCESS ANALYSIS (4) Dahuron  Limit 100    Prereq: 030.101, 171.101   Introduction to chemical and biomolecular engineering and the fundamental principles of chemical process analysis. Formulation and solution of material and energy balances on chemical processes. Reductionist approaches to the solution of complex, multi-unit processes will be emphasized. Introduction to the basic concepts of thermodynamics as well as chemical and biochemical reactions.

Lec.

Sec. 01

02

03

04

MTWTh 3-3:50

Th 4:30-5:20

Th 5-5:50

F 3-3:50

F 4:30-5:20

540.204 (E)

APPLIED PHYSICAL CHEMISTRY (3) Gracias   Prereq: 540.203  Limit 90 Introduction of the methods used to solve thermodynamic problems faced by chemical and biomolecular engineers, including phase and chemical equilibria problems, the thermodynamic properties of interfaces, and the thermodynamics of macromolecules. The basic thermodynamic relationships to describe phase equilibrium of single-component and multicomponent systems are developed. Thermodynamic models for calculating fugacity are presented. Multi-component phase equilibrium problems addressed include liquid-vapor, liquid-liquid, and liquid-liquid-vapor equilibrium. Basic thermodynamic relationships to describe chemical equilibria, the physical chemistry of liquid-liquid and liquid-solid interfaces, and the conformation of biological macro-molecules are also presented.

Sec. 01

MWF 11-11:50

540.304 (E,N)

TRANSPORT PHENOMENA II (4) Drazer   Prereq: 540.303  Limit  90 Dimensional analysis and dimensionless groups. Laminar boundary layers, introduction to turbulent flow. Definition of the friction factor. Macroscopic mass, momentum and mechanical energy balances (Bernouilli’s equation). Metering of fluids. Convective heat and mass transfer. Heat and mass transfer in boundary layers. Correlations for convective heat and mass transfer. Boiling and condensation. Interphase mass transfer.

Sec. 01

MWF 8:40-9:50 MTWF 9-9:50 MWF 8:45-10

540.311 (E) (W)

CHEMICAL ENGINEERING LAB I (6) Katz/Dahuron   Limit 3 per section  Prereq: 540.301, 540.304, 540.306, 540.490 Students are challenged with laboratory projects that are not well-defined and learn to develop an effective framework for approaching experimental work by identifying the important operating variables, deciding how best to obtain them, and using measured or calculated values of these operating variables to predict, carryout, analyze and improve upon experiments. Each student analyzes three of the following four projects: distillation, gas absorption, liquid-liquid extraction and chemical kinetics in a tubular flow reactor and also one of the projects in 540.313. In addition to technical objectives, this course stresses oral and written communication skills and the ability to work effectively in groups. Students will have additional meeting times outside of class.

Sec. 01

02

03

T 1-6pm

Th 1-6pm

M 1-6pm

540.313 (E)
(W)

CHEMICAL AND BIOMOLECULAR ENGINEERING LAB I (6) Limit 16 per section  Gerecht/Staff   Prereq: 540.301, 540.304, 540.306, 540.490Students are challenged with laboratory projects that are not well-defined and learn to develop an effective framework for approaching experimental work by identifying the important operating variables, deciding how best to obtain them, and using measured or calculated values of these operating variables to predict, carryout, analyze and improve upon experiments. Each student analyzes three biomolecular engineering projects and one of the projects in 540.311. In addition to technical objectives, this course stresses oral and written communication skills and the ability to work effectively in groups. Students will have additional meeting times outside of class.

Sec. 01

02

03

04

T 1-6pm

Th 1-6pm

F 1-6pm

M 1-6pm

540.402 (E)

CELL AND MOLECULAR BIOTECHNOLOGY OF MAMMALIAN SYSTEMS (3) Betenbaugh/Konstantopoulos     Limit 35 Course added 3/26/08

  Sec. 01

MW 3-4:15 4:30-5:45pm

540.403 (E)

COLLOIDS AND NANOPARTICLES (3) Bevan Limit 30 Fundamental principles related to interactions, dynamics, and structure in colloidal, nanoparticle, and interfacial systems. Concepts covered include ydrodynamics, Brownian motion, diffusion, sedimentation, electrophoresis, colloidal and surface forces, polymeric forces, aggregation, deposition, and experimental methods. Modern topics elated to colloids in nano- science and technology will be discussed throughout the course with frequent references to recent literature. Course added 4/09/08

  Sec. 01

MWF 10-10:50

540.409 (E,Q)

MODELING, DYNAMICS AND CONTROL OF CHEMICAL AND BIOLOGICAL SYSTEMS (3) Gray    Limit 25 per section   Coreq: 500.303 or a Differential Equations course, 540.203, 540.301, 540.303.  020.305 and 020.306 or equivalent is recommended but not required. Introduction to modeling, dynamics, and control. Unsteady state analysis of biomolecular and chemical process control systems.  State space and Laplace transform techniques, block diagram algebra, and transfer functions.  Feedback and feedforward control. Frequency response and stability analysis.  Model construction for biomolecular and cellular systems including pharmacokinetic modeling, biomolecular modeling using the central dogma of biology/control of gene expression, large scale biosimulation. Introduction to nonlinear dynamics.

  Sec. 01

02

MWF 10-10:50

MWF 10-10:50

540.420 (N)

BUILD-A-GENOME (4) Boeke / Bader / Ostermeier   Perm Req'd Must understand fundamentals of DNA structure, DNA electrophoresis and analysis, Polymerase Chain Reaction (PCR) and must be either a) Experienced with molecular biology lab work or b) Adept at programming with a biological twist. In this combination lecture/laboratory "Synthetic Biology" course students will learn how to make DNA building blocks used in an int'l. project to build the world's first synthetic eukaryotic genome, Saccharomyces cerevisiae v. 2.0. Please study the wiki www.syntheticyeast.org for more details about the project. Following a biotechnology boot-camp, students will have 24/7 access to computational and wet-lab resources and will be expected to spend 15-20 hours per week on this course. Advanced students will be expected to contribute to the computational and biotech infrastructure. Co-listed with 580.420 & 020.420 Successful completion of this course provides 3 credit hours toward the supervised research requirement for Molecular and Cellular Biology majors, or 2 credit hours toward the upper level elective requirement for Biology or Molecular and Cellular Biology majors.
Course added 4/15/08

Sec. 01

MWF 5-6:30pm

540.490

CHEMICAL AND LABORATORY SAFETY (1) Katz   Perm. Req’d.       
Limit 100 per section    This course is meant to provide the student with a basic knowledge of laboratory safety; hazards, regulations, personal protective equipment, good laboratory practice, elementary toxicology, and engineering controls. It has been developed by the Department of Chemical and Biomolecular Engineering to assist with regulatory compliance, minimize hazards, and reduce the severity of any incidents that may occur in the department’s laboratories. The course is a prerequisite of 540.311/540.313. It is required of all Chemical and Biomolecular Engineering undergraduates. In addition once per year a three-hour refresher seminar must be taken by all students involved in laboratory research.

Sec. 01

02

TBA

TBA

540.501

INDEPENDENT STUDY 
Students do a reading course in specialized areas not directly available by lecture courses. Assignments and problems are prescribed by a faculty member.  1-3 credits

540.521

INDEPENDENT RESEARCH
Students do individual projects (or in collaboration with faculty and/or graduate students) in areas basic to chemical engineering.  1-3 credits

540.600

CHEMICAL ENGINEERING SEMINAR Drazer   Limit 100   Lectures are presented on current subjects relevant to chemical engineering. 

Sec. 01

Th 10:30-11:45

540.602

CELL AND MOLECULAR BIOTECHNOLOGY OF MAMMALIAN SYSTEMS (3) Betenbaugh/Konstantopoulos     Limit 35 Course added 3/26/08

  Sec. 01

MW 3-4:15 4:30-5:45pm

540.603

COLLOIDS AND NANOPARTICLES (3) Bevan Limit 30 Fundamental principles related to interactions, dynamics, and structure in colloidal, nanoparticle, and interfacial systems. Concepts covered include ydrodynamics, Brownian motion, diffusion, sedimentation, electrophoresis, colloidal and surface forces, polymeric forces, aggregation, deposition, and experimental methods. Modern topics elated to colloids in nano- science and technology will be discussed throughout the course with frequent references to recent literature. Course added 4/09/08

  Sec. 01

MWF 10-10:50

540.630

THERMODYNAMICS AND STATISTICAL MECHANICS (3) Asthagiri   Limit 30 Course added 4/08/08

  Sec. 01

MW 2-3:30

540.645

MICRO AND NANOTECHNOLOGY:
A RESEARCH PERSPECTIVE Gracias  Limit 12

Sec. 01

F 11-11:50

540.652

FUNDAMENTAL BIOTRANSPORT PHENOMENON  Konstantopoulos/Stebe  Limit 30  This lecture course introduces students to the application of engineering fundamentals from transport and kinetic processes to vascular biology and medicine. The first half of the course addresses the derivation of the governing equations for Newtonian fluids, their solution in the creeping flow limit. The second half of the course considers how these concepts can be used to understand the behavior of a deformable cell near planar surfaces.

Sec. 01

TTh 4-5:20

540.801

GRADUATE RESEARCH

540.803

INDEPENDENT STUDY