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Publications

  • Shilagardi, K., Li, S., Luo, F., Marikar, F, Duan R., Jin, P., Kim, J., Murnen, K., and Chen, E.H. (2013) Actin-propelled invasive membrane protrusions promote fusogenic protein engagement during cell-cell fusionScience 340, 359 (2013); DOI: 10.1126/science. 1234781. [pdf]
    Nature Research Highlight
    JHU news release 
     

  • Duan R, Jin P, Luo F, Zhang G, Anderson N, Chen EH. (2012) Group I PAKs function downstream of Rac to promote podosome invasion during myoblast fusion in vivo. J Cell Biol. 199(1):169-85. [pdf]
     

  • Chen, E.H. (2011) Invasive podosomes and myoblast fusion. In Membrane Fusion, L. V. Chernomordik and M. M. Kozlov, eds. (Elsevier, USA), pp. 235-258. [pdf]

  • Jin, P., Duan, R., Luo, F., Zhang, G., Hong, N., and Chen, E.H. (2011) Competition between Blown fuse and WASP for WIP binding regulates the dynamics of WASP-dependent actin polymerization in vivo. Developmental Cell 20:623-638. [pdf]

  • Sens, K.L., Zhang, S., Jin, P., Duan, R., Zhang, G., Luo, F., Parachini, L., and Chen, E.H. (2010) An invasive podosome-like structure promotes fusion pore formation during myoblast fusion. J. Cell Biol. 191, 1013-1027. [pdf]
    Nature Reviews Molecular Cell Biology Research Highlight
    Journal of Cell Biology podcast
    Journal of Cell Biology news release
    Current Biology Dispatch
    Johns Hopkins University news release

  • Zhang, S., and Chen, E.H. (2008) Ultrastructural analysis of myoblast fusion in Drosophila. In Cell Fusion, E. H. Chen ed. (the Humana Press Inc., New Jersey), pp. 275-297. [pdf]

  • Kim, S., Shilagardi, K., Zhang, S., Hong, S.N., Sens, K.L., Bo, J., Gonzalez, G.A., and Chen, E.H. (2007) A critical function for the actin cytoskeleton in targeted exocytosis of prefusion vesicles during myoblast fusion. Developmental Cell 12, 571-586. [pdf]
    Devevelopmental Cell Preview

  • Chen, E.H., Grote, E., Mohler, W.A., and Vignery, A. (2007) Cell-cell fusion. FEBS Letters 581, 2181-2193. [pdf]

  • Chen, E.H., and Olson, E.N. (2005) Unveiling the mechanisms of cell-cell fusion. Science 308, 369-373. [pdf] 

  • Chen, E.H., and Olson, E.N. (2004) Toward a molecular pathway of myoblast fusion in Drosophila. Trends in Cell Biology 14, 452-460. [pdf]

  • Chen, E.H., Pryce, B.A., Tzeng J.A., Gonzalez, G.A., and Olson, E.N. (2003) Control of myoblast fusion by a guanine nucleotide exchange factor, Loner, and its effector ARF6. Cell 114 , 751-762. [pdf]
    Devevelopmental Cell Preview

  • Chen, E.H., and Olson, E.N. (2001) Antisocial, an intracellular adaptor protein, is required for myoblast fusion in Drosophila. Developmental Cell1, 705-715. [pdf]

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All material contained herein copyright Elizabeth Chen.