Graduate Program: Courses
540.602
Cellular and Molecular Biotechnology of Mammalian Systems
Molecular biology techniques, DNA, RNA, and proteins; control of gene
expression;
microarray technology and proteomics; cell-cell signaling and
communication; cell
adhesion; extracellular matrix; introductory glycobiology. Cell
structure:
membrane, cytoskeleton, organelles, proteins secretion and
degradation. Cell Replication and Death: cell cycle, cell
division, senescence, and apoptosis. Multicellular Systems:
fertilization. Tissue Development: nervous system,
ectoderm (neuronal crest), mesoderm, endoderm metamorphosis,
regeneration, aging. Stem Cell Biology: Adult and fetal stem
cells, germ and embryonic stem cells, cell expansion of
undifferentiated and progenitor cells, differentiation
regulation, and control/engineering of stem cell renewal and
differentiation in vitro.
Gerecht / Fall semester
540.610 Fundamentals of Membrane Science for Filtration Applications
This course focuses on the principles underlying the formation of micro-to-nanostructured membranes applied in a range of modern filtration technologies such as microfiltration, ultrafiltration, nanofiltration, reverse osmosis, pervaporation, gas separation, electrodialysis, hemodialysis, fuel cells, drug delivery, tissue engineering and sensors. Polymeric membranes prepared by phase separation will be examined in detail, while interfacial polymerization and sol-gel processing to prepare thin film composites and ceramic membranes, respectively, will also be studied. The first part of the course will discuss how concepts from thermodynamics, multicomponent diffusion and fluid/solid mechanics are applied to membrane formation theory. The second part will present membrane transport theory, and demonstrate how engineering principles are applied to the various filtration applications and the design of modules.
Prakash / 3 hours, Spring Semester
540.614
Computational protein structure prediction and design
(For description, see 540.414)
Gray / 3 hours, Spring Semester
540.615
Interfacial science with applications to nanoscale systems
Nanostructured materials intrinsically possess large surfacearea
(interface area) to volume ratios. It is this large
interfacial area that gives rise to many of the amazing
properties and technologies associated with nanotechnology.
In this class we will examine how the properties of surfaces,
interfaces, and nanoscale features differ from their
macroscopic behavior. We will compare and contrast fluidfluid
interfaces with solid-fluid and solid-solid interfaces,
discussing fundamental interfacial physics and chemistry,
as well as touching on state-of-the-art technologies.
Frechette / 3 hours, Fall Semester
540.626
(E) Introduction to Biomacromolecules
[For description, see 540.426]
Wirtz
540.630
Thermodynamics and statistical mechanics for chemical and biomolecular
systems
We will develop equilibrium thermodynamics and statistical mechanics
from the unified perspective of entropy maximization subject to
constraints. After a brief review of classical thermodynamics, we will
undertake the study of statistical mechanics leading up to the study of
liquids,
especially liquid water, and of the hydration of (bio)molecules.
Time permitting, we will (a) explore a modern approach of including
quantum chemistry in describing hydration, and (b) understand the
relation between
non-equilibrium work and equilibrium free energies.
Asthagiri / 3 hours, Fall Semester
540.633
Engineering Aspects of Controlled Drug Delivery
[For description see 540.433]
Hanes
540.637
Application of Molecular Evolution to Biotechnology
[For description, see 540.437]
Ostermeier / 3 hours, Spring Semester
540.640
Micro to nanotechnology
[For description, see 540.440]
Gracias
540.652
Fundamentals of Biotransport Phenomena
This lecture course introduces students to the applicationof
engineering fundamentals from transport and kinetic
processes to vascular biology and medicine. The first half
of the course addresses the derivation of the governing
equations for Newtonian fluids, their solution in the
creeping flow limit. The second half of the course considers
how these concepts can be used to understand the
behavior of a deformable cell near planar surfaces.
Drazer / 3 hours, Fall Semester
540.801-816
Graduate Research
1-12 hours
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