1. Identification of the Reactive Electronic State in the Photocycloaddition of Alkenes to Cyclic Enones.
Schuster, D. I.; Greenberg, M. M.; Nunez, I. M.; Tucker, P. C. J. Org. Chem. 1983, 48, 2615.
2. 3,4-Dimethylenefuran, and 3,4-Dimethylenethiophene, Heterocyclic Analogues of the Disjoint Non-Kekulé Hydrocarbon Tetramethyleneethane.
Stone, K. J.; Greenberg, M. M.; Goodman, J. L.; Peters, K. S.; Berson, J. A. J. Am. Chem. Soc. 1986, 108, 8088.
3. The First Magic Angle Spinning NMR Spectrum of a Captive Intermediate: Direct Observation of a Singlet Ground State Biradical, 3,4-Dimethylenefuran.
Zilm, K. W.; Merrill, R. A.; Greenberg, M. M.; Berson, J. A. J. Am. Chem. Soc. 1987, 109, 1567.
4. Identity of 3,4-Dimethylenethiophene Reactive Intermediates From Diazene and Bis-Allene Precursors. Correlation of Singlet Biradical Reactivity in the Tetramethyleneethane and Trimethylenemethane Series.
Greenberg, M. M.; Blackstock, S. C.; Berson, J. A. Tetrahedron Lett. 1987, 28, 4263.
5. Two Dimensional Solid-State NMR of a Captive Intermediate: Structure of the Radical Centers in 3,4-Dimethylenethiophene.
Zilm, K. W.; Merrill, R. A.; Webb, G. G.; Greenberg, M. M.; Berson, J. A. J. Am. Chem. Soc. 1989, 111, 1533.
6. Ground State Multiplicities of 3,4-Dimethylenefuran and 3,4-Dimethylenethiophene. Experimental Tests of Ab Initio and Semiempirical Theories of Heteroatom-Bridged Disjoint Biradicals.
Greenberg, M. M.; Blackstock, S. C.; Stone, K. J.; Berson, J. A. J. Am. Chem. Soc. 1989, 111, 3671.
7. Heterocyclic Aromatic Non-Kekulé Molecules. Synthesis and Solution-Phase Chemistry of the Singlet Biradicals 3,4-Dimethylenefuran and 3,4-Dimethylenethiophene.
Stone, K. J.; Greenberg, M. M.; Blackstock, S. C.; Berson, J. A. J. Am. Chem. Soc. 1989, 111, 3659.
8. Structure of the Carrier of the CPMAS 13C NMR Signal Assigned to 3,4-Dimethylenethio-phene. Multiple Position Labeling and Chemical Trapping in Annealed Glasses.
Greenberg, M. M.; Blackstock, S. C.; Berson, J. A.; Merrill, R. A.; Duchamp, J. C.; Zilm, K. W. J. Am. Chem. Soc. 1991, 113, 2318.
9. Independent Generation of the Major Adduct of Hydroxyl Radical and Thymidine. Examination of Intramolecular Hydrogen Atom Transfer in Competition With Thiol Trapping.
Barvian, M. R.; Greenberg, M. M. Tetrahedron Lett. 1992, 33, 6057.
10. Photochemical Cleavage of Oligonucleotides From Solid Phase Supports.
Greenberg, M. M. Tetrahedron Lett. 1993, 34, 251.
11. Diastereoselective Synthesis of Hydroxylated Products of Thymidine Resulting from Oxidative Stress.
Barvian, M. R.; Greenberg, M. M. J. Org. Chem. 1993, 58, 6151.
12. Cleavage of Oligonucleotides from Solid Phase Supports Using o-Nitrobenzyl Photochemistry.
Greenberg, M. M.; Gilmore, J. L. J. Org. Chem. 1994, 59, 746.
13. Site Specific Incorporation of the Alkaline Labile, Oxidative Stress Product (5R)-5,6-Dihydro-5-hydroxythymidine in an Oligonucleotide.
Matray, T. J.; Greenberg, M. M. J. Am. Chem. Soc. 1994, 116, 6931.
14. Kinetic Analysis of the Rearrangement of a Conformationally Constrained α-Cyclopropyl Benzyl Radical.
Venkatesan, H.; Greenberg, M. M. J. Org. Chem. 1994, 59, 3514.
15. A General Method for the Synthesis of C2'-Deuteriated Ribonucleosides
Cook, G. P.; Greenberg, M. M. J. Org. Chem. 1994, 59, 4704.
16. Photochemical Release of Protected Oligonucleotides Containing 3'-Glycolate Termini.
Greenberg, M. M. Tetrahedron 1995, 51, 29.
17. Benzylic Stabilization as a Mechanistic Tool for Studying Radical Rearrangements.
Venkatesan, H.; Greenberg, M. M. J. Org. Chem. 1995, 60, 1053.
18. Reactivity of the Major Adduct of Thymidine and Hydroxyl Radical Generated Via Photoinduced Single Electron Transfer, and the Role of 1,4-Cyclohexadiene in the Photodeoxygenation Process.
Barvian, M. R.; Barkley, R. M.; Greenberg, M. M. J. Am. Chem. Soc. 1995, 117, 4894.
19. Independent Generation of 5,6-Dihydrothymid-5-yl, and Investigation of Its Ability to Effect Nucleic Acid Strand Scission Via Hydrogen Atom Abstraction.
Barvian, M. R.; Greenberg, M. M. J. Org. Chem. 1995, 60, 1916.
20. Synthesis of Oligonucleotides Containing 3'-Alkyl Carboxylic Acids Using Universal, Photolabile Solid Phase Supports.
Yoo, D. J.; Greenberg, M. M. J. Org. Chem. 1995, 60, 3358.
21. Independent Generation and Reactivity of 5,6-Dihydrothymid-5-yl in Single Stranded Polythymidylate. O2 is Necessary for Strand Scission.
Barvian, M. R.; Greenberg, M. M. J. Am. Chem. Soc. 1995, 117, 8291.
22. The Effects of the Ring Fragmentation Product of Thymidine C5-Hydrate on Phosphodiesterases and Klenow (Exo-) Fragment.
Matray, T. J.; Haxton, K. J.; Greenberg, M. M. Nucleic Acids Research 1995, 23, 4642.
23. Independent Generation and Reactivity of Deoxyurid-1'-yl.
Goodman, B. K.; Greenberg, M. M. J. Org. Chem. 1996, 61, 2.
24. Improved Efficiency and Utility of Photolabile Solid Phase Oligonucleotide Synthesis Supports.
Venkatesan, H.; Greenberg, M. M. J. Org. Chem. 1996, 61, 525.
25. Synthesis of Oligonucleotides Containing 3'-Alkyl Amines Using Universal, Photolabile Solid Phase Supports.
McMinn, D. L.; Greenberg, M. M. Tetrahedron 1996, 52, 3827.
26. A Novel Mechanism for the Formation of Direct Strand Breaks Upon Anaerobic Photolysis of Duplex DNA Containing 5-Bromodeoxyuridine.
Cook, G. P.; Greenberg, M. M. J. Am. Chem. Soc. 1996, 118, 10025.
27. DNA Damage Induced Via 5,6-Dihydrothymid-5-yl in Single Stranded Oligonucleotides.
Greenberg, M. M.; Barvian, M. R.; Cook, G. P.; Goodman, B. K.; Matray, T. J.; Tronche, C.; Venkatesan, H. J. Am. Chem. Soc. 1997, 119, 1828.
28. Synthesis of Oligonucleotides Containing 3'-Alkyl Carboxylic Acids Using a Palladium Labile Solid Phase Synthesis Support.
Matray, T. J.; Yoo, D. J.; McMinn, D. L.; Greenberg, M. M. Bioconjugate Chemistry 1997, 8, 99.
29. C1’ Acylated Derivatives of 2'-Deoxyuridine. Photolabile Precursors of 2’-Deoxyuridin-1’-yl.
Greenberg, M. M.; Yoo, D. J.; Goodman, B. K. Nucleosides & Nucleotides 1997, 16, 33.
30. Synthesis of Oligonucleotides Containing 3'-Alkyl Amines Using N-Isobutyryl Protected Deoxyadenosine Phosphoramidite.
McMinn, D. L.; Greenberg, M. M. Tetrahedron Lett. 1997, 38, 3123.
31. Inhibition of Klenow Fragment (exo-) Catalyzed DNA Polymerization By (5R)-5,6-Dihydro-5-hydroxythymidine and Structural Analogue 5,6-Dihydro-5-methylthymidine.
Greenberg, M. M.; Matray, T. J. Biochemistry 1997, 36, 14071.
32. Efficient Solution Phase Synthesis of Oligonucleotide Conjugates Using Protected Biopolymers Containing 3’-Terminal Alkyl Amines.
McMinn, D. L.; Matray, T. J.; Greenberg, M. M. J. Org. Chem. 1997, 62, 7074.
33. Stereoselective Synthesis of 3'-Deuterated Pyrimidine Nucleosides Via Stereoselective Reduction of a Protected 3-Oxoribose.
Chen, T.; Greenberg, M. M. Tetrahedron Lett. 1998, 39, 1103.
34. The Ring Fragmentation Product of Thymidine C5-Hydrate When Present in DNA is Repaired by the Escherichia Coli Fpg and Nth Proteins.
Jurado, J.; Saparbaev, M.; Matray, T. J.; Greenberg, M. M.; Laval, J. Biochemistry 1998, 37, 7757.
35. Post-Synthetic Conjugation of Protected Oligonucleotides Containing 3'-Alkylamines.
McMinn, D. L.; Greenberg, M. M. J. Am. Chem. Soc. 1998, 120, 3289.
36. Model Studies Indicate That Copper-Phenanthroline Induces Direct Strand Breaks Via β-Elimination of the 2'-Deoxyribonolactone Intermediate Observed in Enediyne Mediated DNA Damage.
Chen, T.; Greenberg, M. M. J. Am. Chem. Soc. 1998, 120, 3815.
37. Release of Superoxide From Nucleoside Peroxyl Radicals, A Double Edged Sword?
Tronche, C.; Tallman, K. A.; Yoo, D. J.; Greenberg, M. M. J. Am. Chem. Soc. 1998, 120, 4903.
38. Optimization and Mechanistic Analysis of Oligonucleotide Cleavage From Palladium Labile Solid Phase Synthesis Supports.
Greenberg, M. M.; Matray, T. J.; Kahl, J. D.; Yoo, D. J.; McMinn, D. L. J. Org. Chem. 1998, 63, 4062.
39. An Orthogonal Solid Phase Support for the Synthesis of Oligonucleotides Containing 3'-Phosphates and Its Application in the Preparation of Photolabile Hybridization Probes.
McMinn, D. L.; Hirsch, R.; Greenberg, M. M. Tetrahedron Lett. 1998, 39, 4155.
40. A High Yielding Method For On-Column Derivatization of Protected Oligodeoxynucleotides and its Application to the Convergent Synthesis of 5',3'-Bis-conjugates.
Kahl, J. D.; McMinn, D. L.; Greenberg, M. M. J. Org. Chem. 1998, 63, 4870.
41. DNA Damage Induced Via Independent Generation of the Radical Resulting From Formal Hydrogen Atom Abstraction From the C1'-Position of a Nucleotide.
Tronche, C.; Goodman, B. K.; Greenberg, M. M. Chemistry & Biology 1998, 5, 263.
42. Direct Evidence For Bimodal DNA Damage Induced By Tirapazamine.
Daniels, J. S.; Gates, K. S.; Tronche, C.; Greenberg, M. M. Chem. Res. Toxicol. 1998, 11, 1254.
43. Solution Phase Bioconjugate Synthesis Using Protected Oligonucleotides Containing 3'-Alkyl Carboxylic Acids.
Kahl, J. D.; Greenberg, M. M. J. Org. Chem. 1999, 64, 507.
44. Convergent Solution-Phase Synthesis of a Nucleopeptide Using a Protected Oligonucleotide.
McMinn, D. L.; Greenberg, M. M. Bioorganic & Med. Chem. Lett. 1999, 9, 547.
45. Introducing Structural Diversity in Oligonucleotides Via Photolabile, Convertible C5-Substituted Nucleotides.
Kahl, J. D.; Greenberg, M. M. J. Am. Chem. Soc. 1999, 121, 597.
46. The Effects of Secondary Structure and O2 on the Formation of Direct Strand Breaks Upon UV-Irradiation of 5-Bromodeoxyuridine-Containing Oligonucleotides.
Cook, G. P.; Chen, T.; Koppisch, A. T.; Greenberg, M. M. Chemistry & Biology 1999, 6, 451.
47. Kinetics and Stereoselectivity of Thiol Trapping of Deoxyuridin-1'-yl in Biopolymers and Their Relationship to the Formation of Premutagenic α-Deoxynucleotides.Hwang, J. -T.; Greenberg, M. M. J. Am. Chem. Soc. 1999, 121, 4311.
48. The Effects of 5R-5,6-Dihydro-5-hydroxythymidine on Duplex DNA Stability and Structure.Sambandam, A.; Greenberg, M. M. Nucleic Acids Research 1999, 27, 3597.
49. Photosensitization of Guanine-Specific DNA Damage by a Cyano-Substituted Quinoxaline Di-N-Oxide.Fuchs, T.; Gates, K. S.; Hwang, J. -T.; Greenberg, M. M. Chem. Res. Toxicol. 1999, 12, 1190.
50. The Reactivity of the 2-Deoxyribonolactone Lesion in Single Stranded DNA and its Implication in Reaction Mechanisms of DNA Damage and Repair.
Hwang, J. -T.; Tallman, K. T.; Greenberg, M. M. Nucleic Acids Research 1999, 19, 3805.
51. Reaction of the Hypoxia-Selective Antitumor Agent Tirapazamine with a C1'-Radical in Single-Stranded and Double-Stranded DNA: The Drug and Its Metabolites Can Serve as Surrogates for Molecular Oxygen in Radical-Mediated DNA-Damage Reactions.Hwang, J. -T.; Greenberg, M. M.; Fuchs, T.; Gates, K. S. Biochemistry 1999, 38, 14248.
52. Synthesis of Modified Oligodeoxyribonucleotides on a Solid-Phase Support Via Derivatization of a Selectively Revealed 2'-Amino-2'-deoxyuridine.Hwang, J. -T.; Greenberg, M. M. Organic Letters 1999, 1, 2021.
53. Investigation of the Origin of the Sequence Selectivity for the 5-Halo-2'-deoxyuridine Sensitization of DNA to Damage by UV-Irradiation.Chen, T.; Cook, G. P.; Koppisch, A. T.; Greenberg, M. M. J. Am. Chem. Soc. 2000, 122, 3861.
54. Independent Generation and Reactivity of 2'-Deoxy-5-methyleneuridin-5-yl, a Significant Reactive Intermediate Produced From Thymidine as a Result of Oxidative Stress.Anderson, A. S.; Hwang, J. -T.; Greenberg, M. M. J. Org. Chem. 2000, 65, 4648.
55. Chemical Evidence for Thiyl Radical Addition to the C6-Position of a Pyrimidine Nucleoside and its Possible Relevance to DNA Damage Amplification.Carter, K. N.; Taverner, T.; Schiesser, C. H.; Greenberg, M. M. J. Org. Chem. 2000, 65, 8375.
56. AlkA Protein is the Third Escherichia Coli Protein Excising a Ring Fragmentation Product of Thymine.Privezentzev, C. V.; Saparbaev, M.; Sambandam, A.; Greenberg, M. M.; Laval, J. Biochemistry 2000, 39, 14263.
57. Synthesis and Deprotection of Oligonucleotides Under Aprotic Conditions.Chen, T. C.; Fu, J.; Greenberg, M. M. Organic Letters 2000, 2, 3691.
58. Synthesis of 2'-Modified Oligodeoxynucleotides via On-Column Conjugation.Hwang, J. -T.; Greenberg, M. M. J. Org. Chem. 2001, 66, 363.
59. The 2-Deoxyribonolactone Lesion Produced in DNA by Neocarzinostatin and Other Damaging Agents Forms Cross-Links with the Base-Excision Repair Enzyme Endonuclease III.Hashimoto, M.; Greenberg, M. M.; Kow, Y. W.; Hwang, J.-T.; Cunningham, R. P. J. Am. Chem. Soc. 2001, 123, 3161.
60. Product Studies and Laser Flash Photolysis on Alkyl Radicals Containing Two Different β-Leaving Groups are Consonant with the Formation of an Olefin Cation Radical.
Bales, B. C.; Horner, J. H.; Huang, X.; Newcomb, M.; Crich, D.; Greenberg, M. M. J. Am. Chem. Soc. 2001, 123, 3623.
61. Oxygen Dependent DNA Damage Amplification Involving 5,6-Dihydrothymidin-5-yl in a Structurally Minimal System.Tallman, K. A.; Greenberg, M. M. J. Am. Chem. Soc. 2001, 123, 5181.
62. Observation and Elimination of N-Acetylation of Oligonucleotides Prepared Using Fast Deprotecting Phosphoramidites and Ultra-Mild Deprotection.
Zhu, Q.; Delaney, M. O.; Greenberg, M. M. Bioorganic & Med. Chem. Lett. 2001, 11, 1105.
63. Direct Measurement of Pyrimidine C6-Hydrate Stability.
Carter, K. N.; Greenberg, M. M. Bioorganic & Med. Chem. 2001, 9, 2341.
64. Synthesis of Oligonucleotides Containing Fapy•dG (N6-(2-Deoxy-α,β-D-erythro-pento-furanosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine).
Haraguchi, K.; Greenberg, M. M. J. Am. Chem. Soc. 2001, 123, 8636.
65. Template Free Segmental Synthesis of Oligonucleotides Containing Nonnative Linkages.
Greenberg, M. M.; Kahl, J. D. J. Org. Chem. 2001, 66, 7151.
66. Studies on N4-(2-Deoxy-D-pentofuranosyl)-4,6-diamino-5-formamidopyrimidine (Fapy•dA) and N6-(2-Deoxy-D-pentofuranosyl)- 6-diamino-5-formamido-4-hydroxypyrimidine (Fapy•dG)
Greenberg, M. M.; Hantosi, Z.; Wiederholt, C. J.; Rithner, C. D. Biochemistry 2001, 40, 15856.
67. Repair of Oxidized Purines and Damaged Pyrimidines by E. coli Fpg Protein. Different Roles of Proline-2 and Lysine-57 Residues.
Saparbaev, M.; Sidorkina, O. M.; Jurado, J.; Privezentzev, C. V.; Greenberg, M. M.; Laval, J. Environmental and Molecular Mutagenesis 2002, 39, 10.
68. Synthesis and Characterization of Oligodeoxynucleotides Containing Formamidopyrimidine Lesions and Nonhydrolyzable Analogues.
Haraguchi, K.; Delaney, M. O.; Wiederholt, C. J.; Sambandam, A.; Hantosi, Z.; Greenberg, M. M. J. Am. Chem. Soc. 2002, 124, 3263.
69. Covalent Trapping of Human DNA Polymerase β by the Oxidative DNA Lesion 2-Deoxyribonolactone.
DeMott, M. S.; Beyret, E.; Bales, B. C.; Hwang, J. T.; Greenberg, M. M.; Demple, B. J. Biol. Chem. 2002, 277, 7637.
70. Fapy•dA Induces Nucleotide Misincorporation Translesionally by a DNA Polymerase.
Delaney, M. O.; Wiederholt, C. J.; Greenberg, M. M. Angew. Chem. Int. Ed. 2002, 41, 771.
71. Fapy•dG Instructs Klenow Exo- to Misincorporate Deoxyadenosine.
Wiederholt, C. J.; Greenberg, M. M. J. Am. Chem. Soc. 2002, 124, 7278.
72. A Minor Groove Binding Copper-Phenanthroline Conjugate Produces Direct Strand Breaks Via β-Elimination of 2-Deoxyribonolactone.
Bales, B. C.; Pitie, M.; Meunier, B.; Greenberg, M. M. J. Am. Chem. Soc. 2002, 124, 9062.
73. Synthesis of Oligonucleotides and Thermal Stability of Duplexes Containing the β-C-Nucleoside Analogue of Fapy•dG.
Delaney, M. O.; Greenberg, M. M. Chem. Res. Toxicol. 2002, 15, 1460.
74. Interaction of DNA Containing Fapy•dA or its C-Nucleoside Analogues with Base Excision Repair Enzymes. Implications for Mutagenesis and Enzyme Inhibition.
Wiederholt, C. J.; Delaney, M. O.; Greenberg, M. M. Biochemistry 2002, 41, 15838.
75. Action of Human Apurinic Endonuclease (Ape1) on C1'-Oxidized Deoxyribose Damage in DNA.
Xu, Y.; DeMott, M. S.; Hwang, J. T.; Greenberg, M. M.; Demple, B. DNA Repair 2003, 2, 175.
76. Transcription Inhibition Using Modified Pentanucleotides.
Hwang, J. T.; Baltasar, F. E.; Cole, D.; Sigman, D. S.; Chen, C. B.; Greenberg, M. M. Bioorganic & Med. Chem. 2003, 11, 2321.
77. Cross-linking of 2-Deoxyribonolactone and its β-Elimination Product by Base Excision Repair Enzymes.
Kroeger, K. M.; Hashimoto, M.; Kow, Y. W.; Greenberg, M. M. Biochemistry 2003, 42, 2449.
78. Independent Generation and Study of 5,6-Dihydro-2'-deoxyuridin-6-yl. A Member of the Major Family of Reactive Intermediates Formed in DNA from the Effects of γ-Radiolysis.
Carter, K. N.; Greenberg, M. M. J. Org. Chem. 2003, 68, 4275.
79. Synthesis of 5,12-Dioxocyclam Nickel (II) Complexes Having Quinoxaline Substituents at the 6 and 13 Positions as Potential DNA Bis-Intercalating and Cleaving Agents.
Hegedus, L. S.; Greenberg, M. M.; Wendling, J. J.; Bullock, J. P. J. Org. Chem. 2003, 68, 4179.
80. Synthesis and Characterization of Oligonucleotides Containing the C4'-Oxidized Abasic Site Produced by Bleomycin and Other DNA Damaging Agents
Kim, J.; Gil, J. M.; Greenberg, M. M. Angew. Chem. Int. Ed. Engl. 2003, 42, 5882.
81. Repair of DNA Containing Fapy•dG and its β-C-Nucleoside Analogue by Formamidopyrimidine DNA Glycosylase and MutY.
Wiederholt, C. J.; Delaney, M. O.; Pope, M. A.; David, S. S.; Greenberg, Μ. Μ. Biochemistry 2003, 42, 9755.
82. Tandem Lesions are the Major Products Resulting From a Pyrimidine Nucleobase Radical.
Carter, K. N.; Greenberg, M. M. J. Am. Chem. Soc. 2003, 125, 13376.
83. In Vitro Effects of a C4'-Oxidized Abasic Site on DNA Polymerases.
Greenberg, M. M.; Weledji, Y. N.; Kroeger, K. M.; Kim, J.; Goodman, M. F. Biochemistry 2004, 43, 2656.
84. Mutagenic Effects of 2-Deoxyribonolactone in E. coli. An Abasic Lesion that Disobeys the A-Rule.
Kroeger, K. M.; Jiang, Y.; Kow, Y. W.; Goodman, M. F.; Greenberg, M. M. Biochemistry 2004, 43, 6723.
85. Repair of Oxidized Abasic Sites by Exonuclease III, Endonuclease IV, and Endonuclease III.
Greenberg, M. M.; Weledji, Y. N.; Kim, J.; Bales, B. C. Biochemistry 2004, 43, 8178.
86. Evidence for Glycosidic Bond Rotation in a Nucleobase Peroxyl Radical and its Effect on Tandem Lesion Formation
Hong, I. S.; Carter, K. N.; Greenberg, M. M. J. Org. Chem. 2004, 69, 6974.
87. Probing the Configurations of Formamidopyrimidines (Fapy•dA, Fapy•dG) in DNA Using Endonuclease IV.
Patro, J.; Haraguchi, K.; Delaney, M. O.; Greenberg, M. M. Biochemistry 2004, 43, 13397.
88. Independent Generation and Characterization of a C2'-Oxidized Abasic Site in Chemically Synthesized Oligonucleotides.
Kim, J.; Weledji, Y. N.; Greenberg, M. M. J. Org. Chem. 2004, 69, 6100.
89. Effects of the C4'-Oxidized Abasic Site on Replication in E. coli. Unusually Large Deletions are Induced by a Small Lesion.
Kroeger, K. M.; Kim, J.; Goodman, M. F.; Greenberg, M. M. Biochemistry 2004, 43, 13621.
90. A Comprehensive Comparison of DNA Replication Past 2-Deoxyribose and its Tetrahydrofuran Analogue in E. Coli.
Kroeger, K. M.; Goodman, M. F.; Greenberg, M. M. Nucleic Acids Res. 2004, 32, 5480.
91. In Vitro Replication and Repair of DNA Containing a C2'-Oxidized Abasic Site.
Greenberg, M. M.; Weledji, Y. N.; Kroeger, K. M.; Kim, J. Biochemistry 2004, 43, 15217.
92. Mild Thermal Generation of 5-(2'-Deoxyuridinyl)methyl Radical From a Phenyl Selenide Precursor..
Hong, I. S.; Greenberg, M. M. Org. Lett. 2004, 6, 5011.
93. Synthesis of Oligonucleotides Containing Fapy•dG (N-(2-Deoxy-α,β-D-erythropentofuranosyl)-N-(2,6-diamino-4-hydroxy-5-formamidopyrimidine)) Using a 5'-Dimethoxytrityl Dinucleotide Phosphoramidite.
Jiang, Y.; Wiederholt, C. J.; Patro, J. N.; Haraguchi, K.; Greenberg, M. M. J. Org. Chem. 2005, 70, 141. (PMID: 15624916)
94. Selective Detection of 2-Deoxyribonolactone in DNA.
Sato, K.; Greenberg, M. M. J. Am. Chem. Soc. 2005, 127, 2806. (PMID: 15740088)
95. Efficient DNA Interstrand Cross-Link Formation From a Nucleotide Radical.
Hong, I. S.; Greenberg, M. M. J. Am. Chem. Soc. 2005, 127, 3692. (PMID: 15771492)
96. The Effect of the 2-Amino Group of 7,8-Dihydro-8-Oxo-2'-Deoxyguanosine on Translesion Synthesis and Duplex Stability
Oka, N.; Greenberg, M. M. Nucleic Acids Res. 2005, 33, 1637. (PMID: 15778433)
97. Excision of Formamidopyrimidine Lesions by Endonucleases III and VIII is Not a Major DNA Repair Pathway in E. coli.
Wiederholt, C. J.; Patro, J. N.; Jiang, Y.; Haraguchi, K.; Greenberg, M. M. Nucleic Acids Res. 2005, 33, 3331. (PMID: 15944451)
98. Mechanistic Studies on DNA Damage by Minor Groove Binding Copper-Phenanthroline Conjugates.
Bales, B. C.; Kodama, T.; Weledji, Y. N.; Pitié, M.; Meunier, B.; Greenberg, M. M. Nucleic Acids Res. 2005, 33, 5371. (PMID: 16186134)
99. Preparation and Analysis of Oligonucleotides Containing the C4'-Oxidized Abasic Site and Related Mechanistic Probes.
Kim, J.; Kreller, C. R.; Greenberg, M. M. J. Org. Chem. 2005, 70, 8122. (PMID: 16277338)
100. DNA Interstrand Cross-link Formation Initiated by Reaction Between Singlet Oxygen and a Modified Nucleotide.
Hong, I. S.; Greenberg, M. M. J. Am. Chem. Soc. 2005, 127, 10510. (PMID: 16045337)
101. Preparation and Analysis of Oligonucleotides Resulting From C5'-Oxidation.
Kodama, T.; Greenberg, M. M. J. Org. Chem. 2005, 70, 9916. (PMID: 16292822)
102. Mutagenic Effects of Abasic and Oxidized Abasic Lesions in Saccharomyces cerevisiae.
Kow, Y. W.; Bao, G.; Minesinger, B.; Jinks-Robertson, S.; Siede, W.; Jiang, Y. L.; Kim, J.; Greenberg, M. M. Nucleic Acids Res. 2005, 33, 6196. (PMID: 16257982)
103. Repair of Formamidopyrimidines in DNA Involves Different Glycosylases.
Hu, J.; de Souza-Pinto, N. C.; Haraguchi, K.; Hogue, B. A.; Jaruga, P.; Greenberg, M. M.; Dizdaroglu, M.; Bohr, V. A. J. Biol. Chem. 2005, 280, 40544. (PMID: 16221681)
104. Oxygen Independent DNA Interstrand Cross-Link Formation by a Nucleotide Radical.
Hong, I. S.; Ding, H.; Greenberg, M. M. J. Am. Chem. Soc. 2006, 128, 485-491. (PMID: 16402835)
105. Replication of an Oxidized Abasic Site in Escherichia coli by a dNTP-Stabilized Misalignment Mechanism that Reads Upstream and Downstream Nucleotides.
Kroeger, K. M.; Kim, J.; Goodman, M. F.; Greenberg, M. M. Biochemistry 2006, 45, 5048-5056. (PMID: 16605273)
106. Genetic Effects of Oxidative DNA Damages: Comparative Mutagenesis of the Imidazole Ring-Opened Formamidopyrimidines (Fapy lesions) and 8-Oxopurines in Simian Kidney Cells.
Kalam, M. A.; Haraguchi, K.; Chandani, S.; Loechler, E. L.; Moriya, M.; Greenberg, M. M.; Basu, A. K. Nucleic Acids Res. 2006, 34, 2305-2315. (PMID: 16679449)
107. Radiosensitization by a Modified Nucleotide that Produces DNA Interstrand Cross-links Under Hypoxic Conditions.
Hong, I. S.; Ding, H.; Greenberg, M. M. J. Am. Chem. Soc. 2006, 128, 2230-2231. (PMID: 16478174)
108. Reactivity of the C2'-Oxidized Abasic Lesion and Its Relevance to Interactions With Type I Base Excision Repair Enzymes.
Greenberg, M. M.; Kreller, C. R.; Young, S. E.; Kim, J. Chem. Res. Toxicol. 2006, 19, 463-468. (PMID: 16544953)
109. Synthesis, DNA Polymerase Incorporation, and Enzymatic Phosphate Hydrolysis of Formamidopyrimidine Nucleoside Triphosphates.
Imoto, S.; Patro, J. N.; Jiang, Y. L.; Oka, N.; Greenberg, M. M. J. Am. Chem. Soc. 2006, 128, 14606-14611. (PMID: 17090045)
110. Use of Fluorescent Sensors to Determine that 2-Deoxyribonolactone is the Major Alkali-Labile Deoxyribose Lesion Produced in Oxidatively Damaged DNA.
Xue, L.; Greenberg, M. M. Angew. Chem. Int. Ed. 2007, 46, 561-564. (PMID: 17154191)
111. Hole Migration is the Major Pathway Involved in Alkali-Labile Lesion Formation in DNA by the Direct Effect of Ionizing Radiation.
Ding, H.; Greenberg, M. M. J. Am. Chem. Soc. 2007, 129, 772-773. (PMID: 17243808)
112. Characterization and Mechanism of Formation of Tandem Lesions in DNA by a Nucleobase Peroxyl Radical.
Hong, I. S.; Carter, K. N.; Sato, K.; Greenberg, M. M. J. Am. Chem. Soc. 2007, 129, 4089-4098. (PMID: 17335214)
113. Facile Quantification of Lesions Derived from 2'-Deoxyguanosine in DNA.
Xue, L.; Greenberg, M. M. J. Am. Chem. Soc. 2007, 129, 7010-7011. (PMID: 17497789)
114. Studies on the Replication of the Ring Opened Formamidopyrimidine, Fapy•dG in E. coli.
Patro, J. N.; Wiederholt, C. J.; Jiang, Y. L.; Delaney, J. C.; Essigmann, J. M.; Greenberg, M. M. Biochemistry 2007, 46, 10202-10212. (PMID: 17691820)
115. Selective Detection and Quantification of Oxidized Abasic Lesions in DNA.
Dhar, S.; Kodama, T.; Greenberg, M. M. J. Am. Chem. Soc. 2007, 129, 8702-8703. (PMID: 17592848)
116. The Human Werner Syndrome Protein Stimulates Repair of Oxidative DNA Base Damage by the DNA Glycosylase Neil1.
Das, A.; Boldogh, I.; Lee, J. W.; Harrigan, J. A.; Hegde, M. L.; Piotrowski, J.; de Souza-Pinto, N.; Ramos, W.; Greenberg, M. M.; Hazra, T. K.; Mitra, S.; Bohr, V. A. J. Biol. Chem. 2007, 282, 26591-26602. (PMID: 17611195)
117. DNA Strand Damage Product Analysis Provides Evidence That the Tumor Cell-Specific Cytotoxin Tirapazamine Produces Hydroxyl Radical and Acts as a Surrogate for O2.
Chowdhury, G.; Junnotula, V.; Daniels, J. S.; Greenberg, M. M.; Gates, K. S. J. Am. Chem. Soc. 2007, 129, 12870-12877. (PMID: 17900117)
118. -Radiolysis Produces Interstrand Cross-links in DNA Involving Thymidine.
Ding, H.; Greenberg, M. M. Chem. Res. Toxicol. 2007, 20, 1623-1628. (PMID: 17939740)
119. Recognition and Repair of Formamidopyrimidines by 8-Oxoguanine Glycosylases.
Krishnamurthy,, N.; Haraguchi, K.; Greenberg, M. M.; David, S. S. Biochemistry 2008, 47, 1043-1050. (PMID: 18154319)
120. DNA Tandem Lesion Repair by Strand Displacement Synthesis and Nucleotide Excision Repair.
Imoto, S.; Bransfield, L. A.; Croteau, D. L.; Van Houten, B.; Greenberg, M. M. Biochemistry 2008, 47, 4306-4316. (PMID: 18341293)
121. Facile SNP Detection Using Bifunctional, Cross-Linking Oligonucleotide Probes.
Peng, X.; Greenberg, M. M. Nucleic Acids Res. 2008, 36: e31. (PMID: 18281702)
122. DNA Polymerase Bypass in vitro and in E. coli of a C-Nucleotide Analogue of Fapy•dG.
Wiederholt, C. J.; Weledji, Y. N.; Delaney, M. O.; Greenberg, M. M. Bioorganic & Med. Chem. 2008, 16, 4029-4034. (PMID: 18242999)
123. Synthesis and Analysis of Oligonucleotides Containing Abasic Site Analogues.
Huang, H.; Greenberg, M. M. J. Org. Chem. 2008, 73, 2695-2703. (PMID: 18324835)
124. Hydrogen Bonding Contributes to the Selectivity of Nucleotide Incorporation Opposite an Oxidized Abasic Lesion by DNA Polymerase.
Huang, H.; Greenberg, M. M. J. Am. Chem. Soc. 2008, 130, 6080-6081. (PMID: 18412345)
125. Self-Promoted DNA Interstrand Cross-link Formation by an Abasic Site.
Sczepanski, J. T.; Jacobs, A. C.; Greenberg, M. M. J. Am. Chem. Soc. 2008, 130, 9646-9647. (PMID: 18593126)
126. Interstrand Cross-link Formation in Duplex and Triplex DNA by Modified Pyrimidines.
Peng, X.; Hong, I. S.; Li, H.; Seidman, M. M.; Greenberg, M. M. J. Am. Chem. Soc. 2008, 130, 10299-10306. (PMID: 18620398)
127. Mechanism of Replication Termination as Revealed by Tus-mediated Polar Arrest of a Sliding Helicase.
Bastia, D.; Zzaman, S.; Krings, G.; Saxena, M.; Peng, X.; Greenberg, M. M. Proc. Natl. Acad. Sci. USA 2008, 105, 12831-12836. (PMID: 18708526)
128. Protein Binding has a Large Effect on Radical Mediated DNA Damage.
Peng, X.; Pigli, Y.; Rice, P. A.; Greenberg, M. M. J. Am. Chem. Soc. 2008, 130, 12890-12891. (PMID: 18778053)
129. Multinuclear NMR and Kinetic Analysis of DNA Interstrand Cross-link Formation.
Ding, H.; Majumdar, A.; Tolman, J. R.; Greenberg, M. M. J. Am. Chem. Soc. 2008, 130, 17981-17987. (PMID: 19053196)
130. Competitive Inhibition of Uracil DNA Glycosylase by a Modified Nucleotide Whose Triphosphate is a Substrate for DNA Polymerase.
Huang, H.; Stivers, J. T.; Greenberg, M. M. J. Am. Chem. Soc. 2009, 131, 1344-1345. (PMID: 19173657)
131. Scope and Mechanism of Interstrand Cross-link Formation by the C4'-Oxidized Abasic Site
Sczepanski, J. T.; Jacobs, A. C.; Majumdar, A.; Greenberg, M. M. J. Am. Chem. Soc. 2009, 131, 11132-11139. (PMID: 19722676)
132. Photochemical Generation and Reactivity of the 5,6-Dihydrouridin-6-yl Radical.
Newman, C. A.; Resendiz, M.; Sczepanski, J. T.; Greenberg, M. M. J. Org. Chem. 2009, 74, 7007-7012. (PMID: 19691299)
133. Double-Strand Break Formation During Nucleotide Excision Repair of a DNA Interstrand Cross-link.
Sczepanski, J. T.; Jacobs, A. C.; Van Houten, B.; Greenberg, M. M. Biochemistry 2009, 48, 7565-7567. (PMID: 19606890)
134. The Mutagenicity of Thymidine Glycol in Escherichia Coli is Increased When it is Part of a Tandem Lesion.
Huang, H.; Imoto, S.; Greenberg, M. M. Biochemistry 2009, 48, 7833-7841. (PMID: 19618962)
135. DNA Interstrand Cross-link Formation by the 1,4-Dioxobutane Abasic Lesion.
Guan, L.; Greenberg, M. M. J. Am. Chem. Soc. 2009, 131, 15225-15231. (PMID: 19807122)
136. Nucleotide Excision Repair of a DNA Interstrand Cross-link Produces Single- and Double-Strand Breaks.
Peng, X.; Ghosh, A. K.; Van Houten, B.; Greenberg, M. M. Biochemistry 2010, 49, 11-19. (PMID: 20000382)
137. DNA Damage and Interstrand Cross-link Formation Upon Irradiation of Aryl Iodide C-Nucleotide Analogues.
Ding, H.; Greenberg, M. M. J. Org. Chem. 2010, 75, 535-544. (PMID: 20067226)
138. Excision of a Lyase Resistant Oxidized Abasic Lesion from DNA.
Wong, R. S.; Sczepanski, J. T.; Greenberg, M. M. Chem. Res. Toxicol. 2010, 23, 766-770. (PMID: 20232790)
139. Direct Strand Scission From a Nucleobase Radical in RNA.
Jacobs, A. C.; Resendiz, M. J. E.; Greenberg, M. M. J. Am. Chem. Soc. 2010, 132, 3668-3669. (PMID: 20184313)
140. Irreversible Inhibition of DNA Polymerase by an Oxidized Abasic Lesion.
Guan, L.; Greenberg, M. M. J. Am. Chem. Soc. 2010, 132, 5004-5005. (PMID: 20334373)
141. A Nucleic Acid-Directed, Red Light-Induced Chemical Reaction.
Fülöp, A.; Xiaohua Peng, X.; Greenberg, M. M.; Mokhir, A. Chem. Commun. 2010, 46, 5659-5661. (PMID: 20574574)
142. Inhibition of Short Patch and Long Patch Base Excision Repair by an Oxidized Abasic Site.
Guan, L.; Greenberg, M. M. Biochemistry 2010, 49, 9904-9910.
143. Rapid DNA-Protein Cross-linking and Strand Scission by an Abasic Site in a Nucleosome Core Particle.
Sczepanski, J. T.; Wong, R. S.; McKnight, J. N.; Bowman, G. D.; Greenberg,, M. M. Proc. Natl. Acad. Sci. USA 2010, 107, 22475-22480.
144. Long Patch Base Excision Repair Compensates for DNA Polymerase Inactivation by the C4'-Oxidized Abasic Site.
Jacobs, A. C.; Kreller, C. R.; Greenberg, M. M. Biochemistry 2011, 50, 136-143.
145. An Oxidized Abasic Lesion as an Intramolecular Source of DNA Adducts.
Guan, L.; Greenberg, M. M. Australian J. Chem. (accepted). Invited article for Athelstan L. J. Beckwith memorial issue.
