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Minimization of Animal Numbers Used to Obtain Valid Results

Non Animal Research Methods and Models

The Antibody Resource Page

Videos from NIH Office of Laboratory Animal Welfare

Educational Resources for Teaching

Alternatives in Education

 

 

Literature Search

Animal Use Alternatives Thesaurus

AWIC Tips for Searching for Alternatives to Animal Research and Testing

Meeting the Information Requirements of the Animal Welfare Act

Alternatives to Pain and Distress

Alternatives to Animal Testing Bibliography produced by the National Library of Medicine.

Humane Endpoints at UCAA

Humane Endpoints at ALTWEB

Pain and Distress at ALTWEB

Search Templates at UCAA

Pain Management Database at ALTWEB

Regulations

Epidemiological Research

Generally provides information frequency, distribution and cause of disease in populations.

Human Subjects Research

They may be moral, legal and safety concerns.

In vitro Systems

Alternatives to Animal Testing and Experimentation

Alternatives to Experimental Animals

Alternatives to Laboratory Animals

Alternatives to Use of Live Vertebrate Animals in Biomedical Research and Testing

In Vitro Animal

Mathematical Approaches

Statistical Design

Statistics

Statistical Tools

Principles of Experimental Design in Biomedical Research. ILAR Journal 43 (4): 2002.

The Design of Animal Experiments: Reducing the Use of Animals in Research Through Better Experimental Design. Festing et al (2002). The Royal Society of Medicine Press Ltd., London, England.

Computer Modeling

These systems simulate biological responses and molecular structure and activity relationships. Data for such simulations are derived from in vivo work.

Animal Model Selection

The Institute for Laboratory Animal Resources publishes the ILAR Journal, which discusses different animal models used in research, teaching and testing.  ILAR also publishes information on sources for research animals and genetic material.

When Rats and Mice Cannot Answer the Question: Nontraditional Animal Models for Laboratory Research. ILAR Journal 45(1); 2004

 

Scientific Considerations

Enhancing humane science

Scientific Arguments for Using Animals

Benefits of Animal Based Science

Why Study Animals?

Ethical Considerations

Click here to link to a discussion of the ethics and use in science.

The Principles of Humane Experimental Technique

Animal and Alternatives in Testing: History, Science and Ethics

Why are Animals Used in Research?

Religious Views on Using Animals

Ethics Penn State

Ethics in Animal Use in Science

Animals and Public Policy, Tufts

US Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training

NASA Principles for the Ethical Care and Use of Animals

Minimizing the Harm Done to Animals Used in Science

Utilization of Services

National Agricultural Library

The Animal Welfare Information Center (AWIC) provides information for improved animal care in research, testing and teaching.  AWIC is part of the National Agricultural Library designated by the federal government to provide information on alternatives. AWIC provides training and is a repository for a broad range of information including audiovisual materials.

 

Audio Visual Materials Related to Animal Care, Use and Welfare

Essentials for Animal Research a Primer for Research Personnel

Animal Use Alternative Thesaurus

Centers for Alternatives

ALTWEB

ALTWEB was produced by the Johns Hopkins Center for Alternatives to Animal Testing (CAAT) in collaboration with governmental, academic and private organizations to provide information on alternatives.  ALTWEB is recognized as the premier site for information on alternatives.  It contains a search engine, pain management database as well as full text documents.

CAAT

The Johns Hopkins Center for Alternatives to Animal Testing works with scientists to find new methods to replace the use of laboratory animals in experiments, reduce the number of animals tested, and refine necessary tests to eliminate pain and distress.

UCCAA

The University of California Center for Animal Alternatives is an excellent source for information on animal alternatives to improve the wellbeing and quality of life of research animals wherever possible, and to optimize their contribution to education and research.

 

The Department of Comparative Medicine maintains a library of audiovisual and print material to assist in your research endeavors involving animals.  Veterinarians in this department will assist in model selection, experimental design and provide appropriate training.

 

The Animal Care and Use Committee has developed an Animal Care and Use website. This site contains resources to support your research and teaching program involving the use of animals.  The Animal Care and Use Committee staff provides training on humane care and use of animals.  The Committee also maintains a small library of relevant audiovisual and printed materials.

NORINA

The Norwegian Reference Center for Laboratory Animal Science and Alternatives has a superb collection of materials for teaching and research. Click here to view materials on their site.

Humane Endpoints

Resources from ALTWEB

Resources from University of California Center for Animal Alternatives

ILAR Journal discusses animal models, humane endpoints and less invasive methods.

Definition of Pain and Distress Reporting Requirements for Laboratory Animals

Humane Endpoints for Animals Used in Biomedical Research and Testing
ILAR journal Vol 41(2) 2000.

Books and Journals

Festing, MFW, Overend, P, Das, RG, Borja, MC and Berdoy, M. The Design of Animal Experiments: Reducing the use of animals in research through better experimental design. Laboratory Animal Handbooks No. 14. The Royal Society of Medicine Press Limited. 2002.

Principles of Experimental Design in Biomedical Research. ILAR Journal 43 (4): 2002.

Alternatives to Laboratory Animals

Alternatives to Experimental Animals

Alternatives to Animal Testing and Experimentation

In Vitro Animal

Journal of Applied Animal Welfare Science

Laboratory Animals online is accessible through Welch Library

Monoclonal Antibody Production

Monoclonal Antibody Production JHU

The Psychological Well-being of Nonhuman Primates

 

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