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Emanuel Horowitz Professor of Materials Science and Engineering Ph.D. Metallo-Organic Polymers, George Washington University, 1963 M.S. Chemistry, George Washington University, 1956 B.S. Chemistry, City College of New York, 1948 |
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How biomaterials perform in the human body depends on their preparation conditions, composition, chemical, mechanical, and physical properties. Professor Horowitz seeks to improve the properties of biomaterials for optimum biocompatibility and function over long periods.
In recent years, he has examined surface modification of orthopedic and dental implants to promote new bone attachment and to anchor and stabilize the implant mechanically. Using a plasma spray procedure, metal and alloy coatings of controlled porosity are deposited on the surface of metallic implants to form a strongly bonded porous surface conducive to bony ingrowth. In some cases a ceramic-like material, calcium hydroxylapatite, is then plasma sprayed onto the previously deposited coating to form a composite, double-layered, interlocked and bonded structure. Prof. Horowitz is interested in the relationship between chemical composition and microstructure of biomaterials and their behavior in the body. The composition of calcium hydroxylapatite was determined using wet chemical analysis, infrared spectroscopy, and X-ray dispersive analysis. X-ray diffraction and infrared spectroscopy were used to determine the microstructure of calcium hydroxylapatite which yielded quantitative data on the degree of crystallinity. The orthopedic and dental devices were implanted in animals and human patients to evaluate their performance in the physiological environment. Animal studies involved X-ray examination and histological assessment of the bone-implant interface. Human patients with implanted orthopedic and dental devices are evaluated by X-ray and diagnostic medical tests. Prof. Horowitz also studies the wear of biomaterials such as ultra-high molecular weight polyethylene and alloys used in joint replacement. |
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Selected Publications
Horowitz, E. "Biomaterials: Past, Present and Future." In Proc 4th Israel Mater Engr Conf. Beer Sheva, Israel, 1988. |
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Hahn, H., E. Horowitz, and J.F. Lillard. "Part II: Ardent III Implant Utilizing Porous Composite Coatings." In The Doctor and Technology, Vol. 23, 117. Prague: Czechoslovakia Medical Society, 1992. Hahn, H., L. Landor, A. Sosna, E. Horowitz, P. Vavík, and F. Denk. "Experimental Implantation of Porous Titanium/Hydroxylapatite Coated Hip Stems." In Joint Cong Soc Arts Sci. Prague: Czechoslovakia Academy of Science and Charles University, 1992. Horowitz, E., H. Hahn, and J.C. Burns. "Dental Implant Composite Porous Coatings: Characterization, Properties, and Clinical Performance." In Proc 3rd Intl Conf Oral Implants Dentistry, 23. Osaka, 1993. Horowitz, E., H. Hahn, and J.F. Lillard. "Clinical Evaluation of composite Porous Coatings for Dental Implants." In Proc 3rd Intl Conf Oral Implants Dentistry, 141. Osaka, 1993. Horowitz, E. and E.P. Mueller. "Regulation of Medical Devices." In An Introduction to Bioceramics, edited by L.L. Hench. River Edge, NJ: World Scientific Publishing Co., 1993. Horowitz, E. & Parr, J. E., Editors, "Characterization and Performance of Calcium Phosphate Coatings for Implants." ASTM STP 1196, ASTM Publ. Code 04-011960-54, Philadelphia, 1994. |
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